DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and snai1

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_989267.1	Gene:	snai1 / 394880	XenbaseID:	XB-GENE-479970	Length:	262	Species:	Xenopus tropicalis

Alignment Length:	244	Identity:	104/244 - (42%)
Similarity:	139/244 - (56%)	Gaps:	7/244 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NLTQLAEVTLSVGPLVTDEVKPLPLYASSD--DDSNYYSHKVFDRRKLRRCTISDSNSCASSSSS 78
            |.::|...|:.:.|.:.|:. |||:....:  ....||:..|:|...|  .|...|......|..
Frog    18 NYSELESQTVYISPFIYDKY-PLPVIPQPEILTTGAYYTPLVWDTSLL--TTFFTSEPDYKKSPI 79

  Fly    79 STSSRQSSEDHLGLQGHSSVHHHHGEQGEILN-STSLLEDEHI-CPECGKKYSTSSNLARHRQTH 141
            |.||...|...|.|...||.....|:..:..: ::|..|.|.. |.:|.|.|||.:.|::|:|.|
Frog    80 SPSSSDDSSKPLDLTSFSSEDDEGGKTSDPPSPASSATEAEKFQCNQCSKSYSTFAGLSKHKQLH 144

  Fly   142 RSIMDKKARHCPYCEKVYVSMPAYSMHVRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKC 206
            .....:|:..|.||||.|||:.|..||:|:|...|.|:.|||.||||||||||||||||||||.|
Frog   145 CDSQARKSFSCKYCEKEYVSLGALKMHIRSHTLPCVCKICGKAFSRPWLLQGHIRTHTGEKPFSC 209

  Fly   207 GVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSC 255
            ..|.:||||:||||||:||||:.|.:.|..|.:.|:..|.|:||||:.|
Frog   210 THCNRAFADRSNLRAHLQTHSDVKKYQCKNCSRTFSRMSLLHKHEETGC 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	9/22 (41%)
		C2H2 Zn finger	121..141	CDD:275368	9/19 (47%)
		zf-C2H2	176..198	CDD:278523	17/21 (81%)
		C2H2 Zn finger	178..198	CDD:275368	16/19 (84%)
		zf-H2C2_2	191..214	CDD:290200	17/22 (77%)
		zf-C2H2	204..226	CDD:278523	14/21 (67%)
		C2H2 Zn finger	206..226	CDD:275368	13/19 (68%)
		zf-H2C2_2	218..242	CDD:290200	12/23 (52%)
		C2H2 Zn finger	234..250	CDD:275368	5/15 (33%)
snai1	NP_989267.1	DUF4764	<97..>156	CDD:318226	17/58 (29%)
		C2H2 Zn finger	124..144	CDD:275370	9/19 (47%)
		C2H2 Zn finger	155..175	CDD:275368	12/19 (63%)
		COG5048	<176..>252	CDD:227381	47/75 (63%)
		C2H2 Zn finger	181..201	CDD:275368	16/19 (84%)
		C2H2 Zn finger	209..229	CDD:275368	13/19 (68%)
		C2H2 Zn finger	237..253	CDD:275368	5/15 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910