DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and Scrt1

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001124042.1	Gene:	Scrt1 / 366951	RGDID:	1306236	Length:	348	Species:	Rattus norvegicus

Alignment Length:	305	Identity:	127/305 - (41%)
Similarity:	156/305 - (51%)	Gaps:	60/305 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PIPEELYNLTQLAEVTLSVGPLVTDEVKPLPL-----------YASSDDD-SNYYSHKVF----- 56
            |.||.:|    .|.|...:||..:....| |.           |.:.|.. |..|:...|
  Rat    63 PSPEPMY----AAAVRGELGPAASGSAPP-PTPRPELATAAGGYINGDAAVSEGYAADAFFITDG 122

  Fly    57 -DRRKLRRCTISDSNSCAS-----------------SSSSSTSSRQSSEDHLGLQGHSSVHHHHG 103
             .|||......:.:.|.||                 .|.|.::||..:....|.:..:.    .|
  Rat   123 RSRRKAANANAASAPSTASVAAPDSDAGGGGGPGTRGSGSGSASRGGTRVGAGTEARAG----PG 183

  Fly   104 EQGEILNSTSLLEDEHICPECGKKYSTSSNLARHRQTHRSIMDKKARHCPYCEKVYVSMPAYSMH 168
            ..|        ....|.|.||||.|:|||||:||:|||||:..:.||.||.|.||||||||.:||
  Rat   184 ATG--------AGGRHACGECGKTYATSSNLSRHKQTHRSLDSQLARRCPTCGKVYVSMPAMAMH 240

  Fly   169 VRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKSNLRAHIQTHSNTKPHT 233
            :.||:...:|..|||.||||||||||:|:|||||||.|..|.|||||:||||||:||||..|...
  Rat   241 LLTHDLRHKCGVCGKAFSRPWLLQGHMRSHTGEKPFGCAHCGKAFADRSNLRAHMQTHSAFKHFQ 305

  Fly   234 CARCGKAFALKSYLYKHEESSCMKNRGGVPGSGAASGNRPPSSPK 278
            |.||.|:|||||||.||.||:|.|        |.|||...|:.|:
  Rat   306 CKRCKKSFALKSYLNKHYESACFK--------GGASGPATPAPPQ 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	15/21 (71%)
		C2H2 Zn finger	121..141	CDD:275368	14/19 (74%)
		zf-C2H2	176..198	CDD:278523	15/21 (71%)
		C2H2 Zn finger	178..198	CDD:275368	15/19 (79%)
		zf-H2C2_2	191..214	CDD:290200	16/22 (73%)
		zf-C2H2	204..226	CDD:278523	15/21 (71%)
		C2H2 Zn finger	206..226	CDD:275368	14/19 (74%)
		zf-H2C2_2	218..242	CDD:290200	14/23 (61%)
		C2H2 Zn finger	234..250	CDD:275368	11/15 (73%)
Scrt1	NP_001124042.1	C2H2 Zn finger	193..213	CDD:275368	14/19 (74%)
		C2H2 Zn finger	224..241	CDD:275371	12/16 (75%)
		COG5048	<245..>313	CDD:227381	44/67 (66%)
		C2H2 Zn finger	250..270	CDD:275368	15/19 (79%)
		C2H2 Zn finger	278..298	CDD:275368	14/19 (74%)
		C2H2 Zn finger	306..322	CDD:275368	11/15 (73%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341379
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D545011at33208
OrthoFinder	1	1.000	-	-		FOG0000984
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1445
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.850