Protein Alignment Kah and Zic2

DIOPT Version :10

• Sequence 1: NP_612040.1
• Gene: Kah / 38072
• FlyBaseID: FBgn0035144
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_001101862.2
• Gene: Zic2 / 361096
• RGDID: 1311174
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 241
• Identity: 77/241 - (31%)
• Similarity: 107/241 - (44%)
• Gaps: 36/241 - (14%)

  Fly    99 HHHHGEQGEILN--STSLLEDEHIC----PE--------CGKKYSTSSNLARHRQTHRSIMDKKA 149
            ||||...|....  ....::.|.||    ||        |.|.:||...|..|.........:::
  Rat   233 HHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHVGGPEQS 297

  Fly   150 RH------CPYCEKVYVSMPAYSMHVRTH--NQGCECQF--CGKRFSRPWLLQGHIRTHTGEKPF 204
            .|      ||...|.:.:......|:|.|  .:...|.|  |||.|:|...|:.|.|||||||||
  Rat   298 NHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPF 362

  Fly   205 KCGV--CEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKH---EESSCMKNRGGVPG 264
            :|..  |::.||:.|:.:.|:..|::.||:.|..|.|::...|.|.||   .|||...:......
  Rat   363 QCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSPQGSESSPAA 427

  Fly   265 SGAASGNRPPS--SPKRQQAEVTSGTISALAPGSPAAAVCAASDSA 308
            |.....:.||.  ||   .||..|.  |.|:|.:.|||..||:.:|
  Rat   428 SSGYESSTPPGLVSP---SAEPQSS--SNLSPAAAAAAAAAAAAAA 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	C2H2 Zn finger	121..141	CDD:275368	9/31 (29%)
		zf-C2H2	176..198	CDD:395048	10/23 (43%)
		C2H2 Zn finger	178..198	CDD:275368	10/21 (48%)
		zf-H2C2_2	191..214	CDD:463886	13/24 (54%)
		zf-C2H2	204..226	CDD:395048	7/23 (30%)
		C2H2 Zn finger	206..226	CDD:275368	6/21 (29%)
		C2H2 Zn finger	234..250	CDD:275368	5/15 (33%)
Zic2	NP_001101862.2	zf_ZIC	249..294	CDD:436441	11/44 (25%)
		C2H2 Zn finger	306..326	CDD:275368	5/19 (26%)
		SFP1	<328..412	CDD:227516	34/83 (41%)
		C2H2 Zn finger	334..356	CDD:275368	10/21 (48%)
		C2H2 Zn finger	364..386	CDD:275368	6/21 (29%)
		C2H2 Zn finger	394..414	CDD:275368	7/19 (37%)