DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and rgr

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001163089.2	Gene:	rgr / 35843	FlyBaseID:	FBgn0267792	Length:	889	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	50/163 - (30%)
Similarity:	66/163 - (40%)	Gaps:	27/163 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 VHH--HHGEQGEILNSTSLLEDEHICPECGKKYSTSSNLARHRQTHRSIMDKKARHCPY----CE 156
            ||.  |.|.|            ..||..|||.:....||..|.:.||       |..||    |:
  Fly   706 VHRSAHDGTQ------------PFICTLCGKGFQMPCNLTVHIRRHR-------RDFPYSCEQCD 751

  Fly   157 KVYVSMPAYSMHVRTH--NQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKSNL 219
            |.:.:....::|:|||  .:...|..|||.|........|.|.|..:..|.|.:|.|.|.:|:..
  Fly   752 KRFATSTEVAIHLRTHTGERPYICDLCGKSFKTWSFFDIHRRRHLNQSTFHCPICAKGFYEKNRF 816

  Fly   220 RAHIQTHSNTKPHTCARCGKAFALKSYLYKHEE 252
            ..|:.:|...:.|.|..|||.|.....|.||.|
  Fly   817 TDHMNSHWAIRKHLCTVCGKTFTTYGNLKKHTE 849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	8/21 (38%)
		C2H2 Zn finger	121..141	CDD:275368	7/19 (37%)
		zf-C2H2	176..198	CDD:278523	7/21 (33%)
		C2H2 Zn finger	178..198	CDD:275368	7/19 (37%)
		zf-H2C2_2	191..214	CDD:290200	7/22 (32%)
		zf-C2H2	204..226	CDD:278523	7/21 (33%)
		C2H2 Zn finger	206..226	CDD:275368	6/19 (32%)
		zf-H2C2_2	218..242	CDD:290200	7/23 (30%)
		C2H2 Zn finger	234..250	CDD:275368	6/15 (40%)
rgr	NP_001163089.2	MADF_DNA_bdg	335..420	CDD:287510
		MADF_DNA_bdg	465..551	CDD:287510
		MADF_DNA_bdg	595..682	CDD:287510
		C2H2 Zn finger	691..711	CDD:275368	2/4 (50%)
		C2H2 Zn finger	719..739	CDD:275368	7/19 (37%)
		zf-H2C2_2	731..756	CDD:290200	10/31 (32%)
		COG5048	742..>824	CDD:227381	23/81 (28%)
		C2H2 Zn finger	747..767	CDD:275368	4/19 (21%)
		zf-H2C2_2	763..784	CDD:290200	9/20 (45%)
		C2H2 Zn finger	775..795	CDD:275368	7/19 (37%)
		C2H2 Zn finger	803..818	CDD:275368	5/14 (36%)
		C2H2 Zn finger	831..851	CDD:275368	9/19 (47%)
		C2H2 Zn finger	859..877	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457118
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840