DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and wor

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_476601.1	Gene:	wor / 34906	FlyBaseID:	FBgn0001983	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	328	Identity:	110/328 - (33%)
Similarity:	149/328 - (45%)	Gaps:	93/328 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TPI--PEEL-----------YNLTQLAEVTLSVGPLVTDEVKPLPLYASSDDDSN---------- 49
            ||:  ||:|           .||..:|...||:..:......| |:....|.::.
  Fly   200 TPLAEPEDLSVTQRRVLSENMNLQNVARALLSMQHMAPQHAPP-PIDMEEDQENQDINQLKIKSS 263

  Fly    50 ---YYSHKVFDRRKLRRCTISDSNSCASSSSSSTSSRQSSEDHLGLQGHSSVHHHH--------- 102
               ||        :.::|     |.|.::             :.||..|...|.:.
  Fly   264 NDLYY--------QCQQC-----NKCYAT-------------YAGLVKHQQTHAYESTEYKIIRS 302

  Fly   103 --GEQGEILNSTSLLEDE------------------------HICPECGKKYSTSSNLARHRQTH 141
              |..|.|::.|....|:                        :.|.:|||.|||.|.|::|:|.|
  Fly   303 QPGGSGAIVDQTEFCTDQASALIQAANVASAQSMQKPVGVPRYHCQDCGKSYSTYSGLSKHQQFH 367

  Fly   142 RSIMD----KKARHCPYCEKVYVSMPAYSMHVRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEK 202
            ....:    ||...|..|:|.|||:.|..||:|||...|:|..|||.||||||||||||||||||
  Fly   368 CPSAEGNQVKKVFSCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEK 432

  Fly   203 PFKCGVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSCMKNRGGVPGSGA 267
            ||.|..|.:||||:||||||:||||:.|.::|..|.|:|:..|.|.||.:|.|...:.|.| ||:
  Fly   433 PFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPTCTKSFSRMSLLAKHLQSGCQTEQSGGP-SGS 496

  Fly   268 ASG 270
            ..|
  Fly   497 GGG 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	11/21 (52%)
		C2H2 Zn finger	121..141	CDD:275368	11/19 (58%)
		zf-C2H2	176..198	CDD:278523	17/21 (81%)
		C2H2 Zn finger	178..198	CDD:275368	16/19 (84%)
		zf-H2C2_2	191..214	CDD:290200	17/22 (77%)
		zf-C2H2	204..226	CDD:278523	14/21 (67%)
		C2H2 Zn finger	206..226	CDD:275368	13/19 (68%)
		zf-H2C2_2	218..242	CDD:290200	13/23 (57%)
		C2H2 Zn finger	234..250	CDD:275368	6/15 (40%)
wor	NP_476601.1	C2H2 Zn finger	270..290	CDD:275368	6/37 (16%)
		C2H2 Zn finger	317..334	CDD:275368	1/16 (6%)
		zf-C2H2	345..367	CDD:278523	11/21 (52%)
		C2H2 Zn finger	347..367	CDD:275368	11/19 (58%)
		PHA00732	379..>417	CDD:177300	18/37 (49%)
		C2H2 Zn finger	382..402	CDD:275368	10/19 (53%)
		zf-C2H2_8	405..482	CDD:292531	50/76 (66%)
		zf-C2H2	406..428	CDD:278523	17/21 (81%)
		C2H2 Zn finger	408..428	CDD:275368	16/19 (84%)
		zf-H2C2_2	421..444	CDD:290200	17/22 (77%)
		zf-C2H2	434..456	CDD:278523	14/21 (67%)
		C2H2 Zn finger	436..456	CDD:275368	13/19 (68%)
		zf-H2C2_2	448..473	CDD:290200	14/24 (58%)
		C2H2 Zn finger	464..481	CDD:275368	7/16 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457087
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740