DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and esg

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_476600.1	Gene:	esg / 34903	FlyBaseID:	FBgn0001981	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	249	Identity:	102/249 - (40%)
Similarity:	139/249 - (55%)	Gaps:	41/249 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PLYASSDDDSNYYSHKVFDRRKLRRCTISDSNSCASSSSSSTSSRQSSEDHLGLQGHSSVHHHHG 103
            |.|:    :::|||.:          :::..:||:||.....|.:..   :|.|..::|   ..|
  Fly   235 PAYS----ENSYYSMR----------SMTPESSCSSSLPEDLSLKHK---NLNLNLNTS---QPG 279

  Fly   104 EQG---------EILNSTSLLEDE-----HICPECGKKYSTSSNLARHRQTHRSIMD----KKAR 150
            ||.         |.:.:.|..:|:     :.||:|.|.|||.|.|.:|:|.|....:    ||:.
  Fly   280 EQAAAKTGDMSPETMPNASAKKDKNQPPRYQCPDCQKSYSTFSGLTKHQQFHCPAAEGNQVKKSF 344

  Fly   151 HCPYCEKVYVSMPAYSMHVRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFAD 215
            .|..|:|.|||:.|..||:|||...|:|..|||.||||||||||||||||||||.|..|.:||||
  Fly   345 SCKDCDKTYVSLGALKMHIRTHTLPCKCNLCGKAFSRPWLLQGHIRTHTGEKPFSCQHCHRAFAD 409

  Fly   216 KSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSCMKNRGGVPGSGAAS 269
            :||||||:||||:.|.::|..|.|.|:..|.|.||.|..|   .||..||.::|
  Fly   410 RSNLRAHLQTHSDIKKYSCTSCSKTFSRMSLLTKHSEGGC---PGGSAGSSSSS 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	11/21 (52%)
		C2H2 Zn finger	121..141	CDD:275368	11/19 (58%)
		zf-C2H2	176..198	CDD:278523	17/21 (81%)
		C2H2 Zn finger	178..198	CDD:275368	16/19 (84%)
		zf-H2C2_2	191..214	CDD:290200	17/22 (77%)
		zf-C2H2	204..226	CDD:278523	14/21 (67%)
		C2H2 Zn finger	206..226	CDD:275368	13/19 (68%)
		zf-H2C2_2	218..242	CDD:290200	13/23 (57%)
		C2H2 Zn finger	234..250	CDD:275368	6/15 (40%)
esg	NP_476600.1	zf-C2H2	309..331	CDD:278523	11/21 (52%)
		C2H2 Zn finger	311..331	CDD:275370	11/19 (58%)
		zf-C2H2	344..366	CDD:278523	10/21 (48%)
		C2H2 Zn finger	346..366	CDD:275368	10/19 (53%)
		zf-C2H2	370..392	CDD:278523	17/21 (81%)
		C2H2 Zn finger	372..392	CDD:275368	16/19 (84%)
		zf-H2C2_2	385..408	CDD:290200	17/22 (77%)
		zf-C2H2	398..420	CDD:278523	14/21 (67%)
		C2H2 Zn finger	400..420	CDD:275368	13/19 (68%)
		C2H2 Zn finger	428..444	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457117
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740