DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kah and SNAI3

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_840101.1	Gene:	SNAI3 / 333929	HGNCID:	18411	Length:	292	Species:	Homo sapiens

Alignment Length:	164	Identity:	81/164 - (49%)
Similarity:	98/164 - (59%)	Gaps:	19/164 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 STSLLEDEHICPE-------------------CGKKYSTSSNLARHRQTHRSIMDKKARHCPYCE 156
            |.:|..|.|..||                   |.|.|.|.:.||||||.|..:...:...|.||:
Human   125 SPTLGPDRHGAPEKLLGAERMPRAPGGFECFHCHKPYHTLAGLARHRQLHCHLQVGRVFTCKYCD 189

  Fly   157 KVYVSMPAYSMHVRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKSNLRA 221
            |.|.|:.|..||:|||...|.|:.|||.||||||||||:||||||||:.|..|.:||||:|||||
Human   190 KEYTSLGALKMHIRTHTLPCTCKICGKAFSRPWLLQGHVRTHTGEKPYACSHCSRAFADRSNLRA 254

  Fly   222 HIQTHSNTKPHTCARCGKAFALKSYLYKHEESSC 255
            |:||||:.|.:.|.||.|.|:..|.|.:||||.|
Human   255 HLQTHSDAKKYRCRRCTKTFSRMSLLARHEESGC 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	13/40 (33%)
		C2H2 Zn finger	121..141	CDD:275368	12/38 (32%)
		zf-C2H2	176..198	CDD:278523	16/21 (76%)
		C2H2 Zn finger	178..198	CDD:275368	15/19 (79%)
		zf-H2C2_2	191..214	CDD:290200	15/22 (68%)
		zf-C2H2	204..226	CDD:278523	13/21 (62%)
		C2H2 Zn finger	206..226	CDD:275368	13/19 (68%)
		zf-H2C2_2	218..242	CDD:290200	14/23 (61%)
		C2H2 Zn finger	234..250	CDD:275368	7/15 (47%)
SNAI3	NP_840101.1	SNAG domain. /evidence=ECO:0000250	1..20
		C2H2 Zn finger	154..174	CDD:275370	10/19 (53%)
		C2H2 Zn finger	185..205	CDD:275368	10/19 (53%)
		COG5048	<206..>278	CDD:227381	45/71 (63%)
		C2H2 Zn finger	211..231	CDD:275368	15/19 (79%)
		C2H2 Zn finger	239..259	CDD:275368	13/19 (68%)
		C2H2 Zn finger	267..283	CDD:275368	7/15 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810