DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kah and scrt-1

DIOPT Version :9

Sequence 1:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_491001.2	Gene:	scrt-1 / 183848	WormBaseID:	WBGene00016948	Length:	178	Species:	Caenorhabditis elegans

Alignment Length:	173	Identity:	79/173 - (45%)
Similarity:	94/173 - (54%)	Gaps:	50/173 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 SLLEDEHICPECGKKYSTSSNLARHRQTHRSIMDKKARHCPY--CEKVYVSMPAYSMH------- 168
            ||:|      |..|||::...|.               ..||  ......|:|::|:|
Worm    23 SLIE------EVQKKYNSQVRLI---------------PIPYLPASSSSPSLPSFSLHSDSPSLS 66

  Fly   169 --------------------VRTHNQGCECQFCGKRFSRPWLLQGHIRTHTGEKPFKCGVCEKAF 213
                                ..|.:..|:|:.|||||||.||||||:|||||||||:|.:|.|.|
Worm    67 PSTTVTSYSTPSSPDGKQLKFATCSPVCQCKVCGKRFSRQWLLQGHLRTHTGEKPFQCEICSKRF 131

  Fly   214 ADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYKHEESSCM 256
            ||||||||||||||.||||.|.||||:|||||||.|||||.|:
Worm   132 ADKSNLRAHIQTHSGTKPHKCPRCGKSFALKSYLSKHEESKCL 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	5/21 (24%)
		C2H2 Zn finger	121..141	CDD:275368	5/19 (26%)
		zf-C2H2	176..198	CDD:278523	16/21 (76%)
		C2H2 Zn finger	178..198	CDD:275368	15/19 (79%)
		zf-H2C2_2	191..214	CDD:290200	16/22 (73%)
		zf-C2H2	204..226	CDD:278523	16/21 (76%)
		C2H2 Zn finger	206..226	CDD:275368	15/19 (79%)
		zf-H2C2_2	218..242	CDD:290200	19/23 (83%)
		C2H2 Zn finger	234..250	CDD:275368	12/15 (80%)
scrt-1	NP_491001.2	zf-C2H2	94..116	CDD:278523	16/21 (76%)
		C2H2 Zn finger	96..116	CDD:275368	15/19 (79%)
		zf-H2C2_2	109..132	CDD:290200	16/22 (73%)
		C2H2 Zn finger	124..144	CDD:275368	15/19 (79%)
		zf-H2C2_2	136..160	CDD:290200	19/23 (83%)
		C2H2 Zn finger	152..168	CDD:275368	12/15 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159580
Domainoid	1	1.000	46	1.000	Domainoid score	I8201
eggNOG	1	0.900	-	-		E1_KOG2462
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000984
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3156
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.730