Protein Alignment Ppm1 and PPM1H

DIOPT Version :9

• Sequence 1: NP_612039.1
• Gene: Ppm1 / 38071
• FlyBaseID: FBgn0035143
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_065751.1
• Gene: PPM1H / 57460
• HGNCID: 18583
• Length: 514
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 77/370 - (20%)
• Similarity: 142/370 - (38%)
• Gaps: 136/370 - (36%)

  Fly    54 FFAVYDGHGGASVAKYAGKHLHKFITKR----------------------PE------------- 83
            :::::|||.|:..|..|.:.|...||::                      ||
Human   146 YWSLFDGHAGSGAAVVASRLLQHHITEQLQDIVDILKNSAVLPPTCLGEEPENTPANSRTLTRAA 210

  Fly    84 -------------------YRDNSIE------VALKKAFLDFDREMLQNGSLDEQTAGCTAIVVL 123
                               :.:..|.      .||:.||.:.|.::.:..|....:.||||::|:
Human   211 SLRGGVGAPGSPSTPPTRFFTEKKIPHECLVIGALESAFKEMDLQIERERSSYNISGGCTALIVI 275

  Fly   124 IRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMA--------------------- 167
            ....:||.|||||||||...:|.:..:|.:..|...::..:.:|
Human   276 CLLGKLYVANAGDSRAIIIRNGEIIPMSSEFTPETERQRLQYLAFMQPHLLGNEFTHLEFPRRVQ 340

  Fly   168 --------------SGGW---------VEF---------NRVNGNLALSRALGDF---IYKKNLL 197
                          ..||         ::|         .||...:.::|.|||.   ::..|:.
Human   341 RKELGKKMLYRDFNMTGWAYKTIEDEDLKFPLIYGEGKKARVMATIGVTRGLGDHDLKVHDSNIY 405

  Fly   198 KTPEEQIVTAYPDVEVLDITE----DLEFVLLACDGIWDVMSNFEVCQFVHKRIR--DGMEPE-- 254
            ..|   .:::.|:|.:.|:::    ..:.::||.||:|||:||.||.:.:.:.:.  |..:|.
Human   406 IKP---FLSSAPEVRIYDLSKYDHGSDDVLILATDGLWDVLSNEEVAEAITQFLPNCDPDDPHRY 467

  Fly   255 -LICEELM---NSCLSPDG---HTGNVG-GDNMTVILVCLLH-NK 290
             |..::|:   ...|...|   ....:| ||:::|.::.|:| ||
Human   468 TLAAQDLVMRARGVLKDRGWRISNDRLGSGDDISVYVIPLIHGNK 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppm1	NP_612039.1	PP2Cc	22..286	CDD:238083	73/363 (20%)
PPM1H	NP_065751.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	109..135
		PP2Cc	143..507	CDD:238083	73/363 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144731
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840