Protein Alignment Ppm1 and PPM1G

DIOPT Version :9

• Sequence 1: NP_612039.1
• Gene: Ppm1 / 38071
• FlyBaseID: FBgn0035143
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_817092.1
• Gene: PPM1G / 5496
• HGNCID: 9278
• Length: 546
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 145/525 - (27%)
• Similarity: 188/525 - (35%)
• Gaps: 225/525 - (42%)

  Fly     1 MGQTLSEPVTTK---DTACCANASYRVGSSCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHG 62
            ||..||:|.|.|   |...........|.|.||||||.|||||..|..|  |.:.|.|:||||||
Human     1 MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPEL--DSETAMFSVYDGHG 63

  Fly    63 GASVAKYAGKHLHKFITKRPEYRDNSIEVALKKAFLDFD-------------------------- 101
            |..||.|..|:|...|..:..|::..::.||:.|||..|
Human    64 GEEVALYCAKYLPDIIKDQKAYKEGKLQKALEDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDEK 128

  Fly   102 -------------------------REML------------------------------------ 105
                                     .|:|
Human   129 EKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCHKGPPHSKSGGGTGEEPGSQGLNGEAGPE 193

  Fly   106 ---------QNG----------------------------------------------------- 108
                     :||
Human   194 DSTRETPSQENGPTAKAYTGFSSNSERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFE 258

  Fly   109 -SLDE------------------------------------------------------------ 112
             |.||
Human   259 DSEDESDEAEEEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMVPGMEGKEEP 323

  Fly   113 -QTAGCTAIVVLIRERRLYCANAGDSRAIACISGMVHALSVDHKPNDAKESKRIMASGGWVEFN- 175
             ..:|.||:|.|||.::|..|||||||.:...:|....:|.||||.|..|..||..:||.|..:
Human   324 GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDG 388

  Fly   176 RVNGNLALSRALGDFIYKKNLLKTPEEQIVTAYPDVEVLDITEDLEFVLLACDGIWDVMSNFEVC 240
            ||||.|.||||:||..||:|....||||:::|.||::||.:|:|.||:::||||||:|||:.||.
Human   389 RVNGGLNLSRAIGDHFYKRNKNLPPEEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVV 453

  Fly   241 QFVHKRIRDGME-PEL-----ICEELMNSCLSPDGHTGNVGGDNMTVILVCLLHNKSYEDLAVRC 299
            .|:..:|....| .||     |.|||::.||:||......|.||||.|::|.....:.| |...
Human   454 DFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTAE-LQPE- 516

  Fly   300 GGKRK 304
            .||||
Human   517 SGKRK 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppm1	NP_612039.1	PP2Cc	22..286	CDD:238083	130/481 (27%)
PPM1G	NP_817092.1	PP2Cc	25..>110	CDD:214625	38/86 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..139		0/22 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..328		5/166 (3%)
		PP2Cc	<324..505	CDD:238083	85/180 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	512..546		6/12 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D957254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1847
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.720