DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppm1 and PPM1K

DIOPT Version :9

Sequence 1:NP_612039.1 Gene:Ppm1 / 38071 FlyBaseID:FBgn0035143 Length:352 Species:Drosophila melanogaster
Sequence 2:NP_689755.3 Gene:PPM1K / 152926 HGNCID:25415 Length:372 Species:Homo sapiens


Alignment Length:281 Identity:89/281 - (31%)
Similarity:130/281 - (46%) Gaps:51/281 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 VGSSCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITK-RPEYRDN 87
            ||.:...|.|.:.|| ......|.|  :..:|||||||||.:.|.:...|:.|.|.. .|  ::.
Human    95 VGCASQIGKRKENED-RFDFAQLTD--EVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLP--KEK 154

  Fly    88 SIEVALKKAFLDFDREMLQNGSLDEQ----TAGCTAIVVLIRER-RLYCANAGDSRAIACISGMV 147
            ::|..|..|||:.|:....:..|...    |:|.||.|.|:|:. .|..|:.||||||.|..|..
Human   155 NLETLLTLAFLEIDKAFSSHARLSADATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKP 219

  Fly   148 HALSVDHKPNDAKESKRIMASGGWVEFN-----RVNGNLALSRALGDFIYKKNLLKTPEEQIVTA 207
            ..|::||.|....|.:||...||:|.:|     .|||.||::|::||..     |||..   |.|
Human   220 MKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLD-----LKTSG---VIA 276

  Fly   208 YPDVEVLDITE-DLEFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEPELICEELMNSCLSPDGHT 271
            .|:.:.:.:.. |..|::|..|||..::::.|:|.||                  |.|..|:...
Human   277 EPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFV------------------NQCHDPNEAA 323

  Fly   272 GNV--------GGDNMTVILV 284
            ..|        ..||.|.::|
Human   324 HAVTEQAIQYGTEDNSTAVVV 344

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ppm1NP_612039.1 PP2Cc 22..286 CDD:238083 89/281 (32%)
PPM1KNP_689755.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 34..55
PP2Cc 95..346 CDD:238083 89/281 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0631
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53745
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.820

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