Protein Alignment Ppm1 and PPM1L

DIOPT Version :9

• Sequence 1: NP_612039.1
• Gene: Ppm1 / 38071
• FlyBaseID: FBgn0035143
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_640338.2
• Gene: PPM1L / 151742
• HGNCID: 16381
• Length: 360
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 94/291 - (32%)
• Similarity: 149/291 - (51%)
• Gaps: 38/291 - (13%)

  Fly    21 SYRVGSSCMQGWRVDMEDAHTHILSLPDDPQAAFFAVYDGHGGASVAKYAGKHLHKFITKR-PEY 84
            ::.|....:||.|..|||....:..|.:....:.|.::|||||.:.|:|....|.:.:.:. .:|
Human    90 NHNVAVYSIQGRRDHMEDRFEVLTDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDY 154

  Fly    85 ---RDNSI---EVALKKAFLDFDREMLQNGSLDEQTAGCTAIVVLIRERRLYCANAGDSRAIAC- 142
               ::||:   :..|::..|..|||||:..::....||.|.::.|:.::.|..||.||||.:.|
Human   155 EKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCD 219

  Fly   143 ISGMVHALSVDHKPNDAKESKRIMASGGWVEFN---RVNGNLALSRALGDFIYKKNLLKTPEEQI 204
            ..|....||.||||...||.|||..:||::.||   ||.|.||:||:|||:.. |||      .:
Human   220 KDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPL-KNL------NV 277

  Fly   205 VTAYPDVEVLDITE-DLEFVLLACDGIWDVMSNFEVCQFVHKRIRDGMEP-----ELICEELMNS 263
            |...||:...|:.: ..||::||.||:||..||.|..:|:.:|:.   ||     .::.:.....
Human   278 VIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKERLD---EPHFGAKSIVLQSFYRG 339

  Fly   264 CLSPDGHTGNVGGDNMTVILVCLLHNKSYED 294
            |           .||:||::|...::...|:
Human   340 C-----------PDNITVMVVKFRNSSKTEE 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppm1	NP_612039.1	PP2Cc	22..286	CDD:238083	93/280 (33%)
PPM1L	NP_640338.2	PP2Cc	93..351	CDD:238083	93/278 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53745
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820