DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hipk and AME3

DIOPT Version :9

Sequence 1:	NP_001369036.1	Gene:	Hipk / 38070	FlyBaseID:	FBgn0035142	Length:	1409	Species:	Drosophila melanogaster
Sequence 2:	NP_194992.1	Gene:	AME3 / 829401	AraportID:	AT4G32660	Length:	400	Species:	Arabidopsis thaliana

Alignment Length:	400	Identity:	129/400 - (32%)
Similarity:	198/400 - (49%)	Gaps:	68/400 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 KVATSGGHAN----TQPPSKRSSSGADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKR 212
            |.|...||.:    ..||.:  ....||.|.....:   :|:..|::|..:|.||||:|::||.|
plant    32 KRAVIKGHGSDGRILSPPLR--DDDRDGHYVFSLRD---NLTPRYKILSKMGEGTFGRVLECWDR 91

  Fly   213 GTSEIVAIKILKNHPSYARQGQIEVSILSRLSQENADEFNFVRAFECFQHKNHTCLVFEMLEQNL 277
            .|.|.|||||:::...|.....||:.:|.:|.:.:......|:....|.::||.|:|||.|..:|
plant    92 DTKEYVAIKIIRSIKKYRDAAMIEIDVLQKLVKSDKGRTRCVQMKNWFDYRNHICIVFEKLGPSL 156

  Fly   278 YDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLV--DPVRQP-------- 332
            :||||:||:|..||..:|....|:|.::..:.:|.|:|.|||||||:||  :.|:.|
plant   157 FDFLKRNKYSAFPLALVRDFGCQLLESVAYMHELQLVHTDLKPENILLVSSENVKLPDNKRSAAN 221

  Fly   333 ---YR-------VKVIDFGSASHVSKTVC-----NTYLQSRYYRAPEIILGLPFCEAIDMWSLGC 382
               :|       :|:|||||      |||     ::.:|:|:||:||:||||.:....|:||:||
plant   222 ETHFRCLPKSSAIKLIDFGS------TVCDNRIHHSIVQTRHYRSPEVILGLGWSYQCDLWSIGC 280

  Fly   383 VVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASK-TSKFFYRDVDSTYPFWRLKTTEE 446
            ::.||..|..|:......:.:..:.:..|...|||...||: ..|:|.|.....:|
plant   281 ILFELCTGEALFQTHDNLEHLAMMERALGPLPEHMTRKASRGAEKYFRRGCRLNWP--------- 336

  Fly   447 HEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTD--RREFIDLLKRMLTIDQERRL 509
             |...:.:|..|.|.:....|               ::::..|  |..|.|||..:|..|...||
plant   337 -EGANSRESIRAVKRLDRLKD---------------MVSKHVDNTRSRFADLLYGLLAYDPSERL 385

  Fly   510 TPAEALNHSF 519
            |..|||:|.|
plant   386 TANEALDHPF 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	118/355 (33%)
Hipk	NP_001369036.1	PHA03378	<1080..1327	CDD:223065
AME3	NP_194992.1	PKc_CLK	58..396	CDD:271036	120/371 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810