Protein Alignment Hipk and dyrk4

DIOPT Version :10

• Sequence 1: NP_001369036.1
• Gene: Hipk / 38070
• FlyBaseID: FBgn0035142
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: XP_009296230.2
• Gene: dyrk4 / 564976
• ZFINID: ZDB-GENE-091015-3
• Length: 644
• Species: Danio rerio
• Alignment Length: 370
• Identity: 136/370 - (36%)
• Similarity: 197/370 - (53%)
• Gaps: 50/370 - (13%)

  Fly   165 PSKRSSSGADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKILKNHPSY 229
            |.........|.|..|.|:   .:...|||||.:|:|:||||:||....|:|.|||||::|...:
Zfish   198 PQNAGYDDEHGSYLKVLHD---HIGYRYEVLEVIGKGSFGQVLKCLDHKTNETVAIKIIRNKKRF 259

  Fly   230 ARQGQIEVSILSRLSQENADE-FNFVRAFECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKY 293
            ..|..:|:.||..:.:.:.|. .|.:...|.|..:||.|:.||:|..|||:.:|:|.|....|..
Zfish   260 HHQALVELKILDAVRRRDRDNCHNVIHMKEYFYFRNHLCISFELLGANLYELIKKNNFQGFSLGL 324

  Fly   294 IRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCNTYLQSR 358
            ||.....:|..|..|.:..:||.|||||||:|..  |....:||:||||:.:..:.| .||:|||
Zfish   325 IRRFAHSLLKCLQMLHKEKIIHCDLKPENILLSQ--RGQGNIKVVDFGSSCYEQQRV-YTYIQSR 386

  Fly   359 YYRAPEIILGLPFCEAIDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASK 423
            :||:||:|||.|:..|||||||||::|||:.|:||:||.||.:||..|.:..|||....:.:||:
Zfish   387 FYRSPEVILGHPYSMAIDMWSLGCILAELYTGYPLFPGESEVEQIACIMEIMGLPPNDFVQTASR 451

  Fly   424 TSKFF-----YRDVDSTYPFWRLKTTEEHEAETNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQL 483
            ...||     .|::                  ||:|.|:.|               |:..:...:
Zfish   452 RRLFFDSKGNPRNI------------------TNSKGKKHR---------------PSSKDLASV 483

  Fly   484 LAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSFT---RLTHL 525
            |  ||:...|:|.::|.|..|..:|:||.||:.|.:.   ||..|
Zfish   484 L--KTNDPLFLDFIQRCLVWDPTKRMTPDEAMQHEWITEGRLNRL 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	128/333 (38%)
		PHA03378	<1080..1327	CDD:223065
dyrk4	XP_009296230.2	None