DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hipk and C36B7.1

DIOPT Version :9

Sequence 1:	NP_001369036.1	Gene:	Hipk / 38070	FlyBaseID:	FBgn0035142	Length:	1409	Species:	Drosophila melanogaster
Sequence 2:	NP_509199.1	Gene:	C36B7.1 / 183253	WormBaseID:	WBGene00016464	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	382	Identity:	103/382 - (26%)
Similarity:	166/382 - (43%)	Gaps:	73/382 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   175 GDY---QLVQHEV-LYSL-------------SAEYEVLEFLGRGTFGQVVKCWKRGTSEIVAIKI 222
            |||   ....||: :::|             |..|.:.|.|..|.:.||.:|..:.|.:.|.||:
Worm    97 GDYGSKNQTNHELGIFTLPNGSYCFKEGDHISYRYSIDEVLSSGYYAQVFRCTDKKTDKKVCIKL 161

  Fly   223 LKNHPSYARQGQIEVSILSRLSQEN-ADEFNFVRAFECFQHKNHTCLVFEMLEQNLYDFL-KQNK 285
            ...:.|...:   |..||.|:.|.| .:..|.||..:....:.|..:|.|..:.:|..:| .::|
Worm   162 KNRNLSTTYE---ETIILLRIHQLNRQNNSNCVRMLDYDHFRGHHFIVLENYQTDLASYLCGRSK 223

  Fly   286 FSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTV 350
            .:  |.:|| |:::.::..|..|.|..:||.||||.|::|.:..|.  .:|:.|||.::.|::..
Worm   224 LT--PREYI-PMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWNRN--NLKLTDFGLSTFVNQGP 283

  Fly   351 CNTYLQSRYYRAPEIILGLPFCEA-----IDMWSLGCVVAELFLGWPLYPGSSEFDQIRYISQTQ 410
            .....|:.||:|||:     ||:.     ||:||||||.||:..|.||:.|.:.|||...|.:..
Worm   284 FFRDYQTLYYKAPEV-----FCQGKVSVEIDIWSLGCVAAEIVRGTPLFVGDNYFDQFALIQEFF 343

  Fly   411 GLPTEHMLNSASKTSKFFYRDVDSTYPF------W-------RLKTTEEHEAETNTKSKEARKYI 462
            |.|:..:.|:.....:|:     :.|.|      |       |....|.|....:...|...
Worm   344 GKPSRKLFNTWGGIHQFY-----TEYFFPRHCFEWLNPFNGDRTMEIEPHYKLAHPSRKPPL--- 400

  Fly   463 FNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHSF 519
                    ..::.:.|.||       :::.....|.|....|...|:..:..|||.|
Worm   401 --------TSSLVSKLPGG-------NQKFLARFLMRCFEWDPTERIKSSFILNHPF 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	96/348 (28%)
Hipk	NP_001369036.1	PHA03378	<1080..1327	CDD:223065
C36B7.1	NP_509199.1	PKc_like	117..443	CDD:389743	97/362 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810