Protein Alignment Hipk and Clk4

DIOPT Version :9

• Sequence 1: NP_001369036.1
• Gene: Hipk / 38070
• FlyBaseID: FBgn0035142
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: XP_017169732.1
• Gene: Clk4 / 12750
• MGIID: 1098551
• Length: 510
• Species: Mus musculus
• Alignment Length: 464
• Identity: 129/464 - (27%)
• Similarity: 206/464 - (44%)
• Gaps: 115/464 - (24%)

  Fly    80 STSSVAAAATS-KRKRQTDCDCGCVDSYNSSHGPPVQQDSSAAAGAGSVGSKAGSGPGPDGIGPI 143
            |.|||.:..:| ||||...|         :||
Mouse   131 SKSSVRSRRSSPKRKRNRPC---------ASH--------------------------------- 153

  Fly   144 SSLKTAHTKVATSGGHANTQPPSKRSSSGADGDYQLVQHEVLYS---LSAEYEVLEFLGRGTFGQ 205
                .:|:|     .|..     |||.|..|.:   ..|.:..|   |.|.||:::.||.|.||:
Mouse   154 ----QSHSK-----SHRR-----KRSRSIEDDE---EGHLICQSGDVLRARYEIVDTLGEGAFGK 201

  Fly   206 VVKCWKRGTSEI-VAIKILKNHPSYARQGQIEVSILSRLSQENADE-FNFVRAFECFQHKNHTCL 268
            ||:|...|...: ||:||:||...|....:.|:.:|..|:..:.:. |..|:..|.|.|..|.|:
Mouse   202 VVECIDHGMDGLHVAVKIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCI 266

  Fly   269 VFEMLEQNLYDFLKQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLV------- 326
            |||:|..:.|||:|:|.|.|..:.:||.:..|:..::..|....|.|.|||||||:.|
Mouse   267 VFELLGLSTYDFIKENSFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYVVK 331

  Fly   327 --DPVRQPYR------VKVIDFGSASHVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCV 383
              ..:::..|      :||:|||||::..:. .:|.:.:|:|||||:||.|.:.:..|:||:||:
Mouse   332 YNSKMKRDERTLKNTDIKVVDFGSATYDDEH-HSTLVSTRHYRAPEVILALGWSQPCDVWSIGCI 395

  Fly   384 VAELFLGWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRDVDSTYPFWRLKTTEEHE 448
            :.|.:||:.::......:.:..:.:..|....||:....|...|.:..:|     |     :||.
Mouse   396 LIEYYLGFTVFQTHDSKEHLAMMERILGPIPAHMIQKTRKRKYFHHNQLD-----W-----DEHS 450

  Fly   449 AE---TNTKSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLT 510
            :.   ...:.|..::::. |.|:                    :..:..||::|||..|..||:|
Mouse   451 SAGRYVRRRCKPLKEFML-CHDE--------------------EHEKLFDLVRRMLEYDPARRIT 494

  Fly   511 PAEALNHSF 519
            ..|||.|.|
Mouse   495 LDEALQHPF 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	105/348 (30%)
		PHA03378	<1080..1327	CDD:223065
Clk4	XP_017169732.1	PKc_CLK1_4	175..504	CDD:271115	109/361 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810