Protein Alignment Hipk and Clk2

DIOPT Version :9

• Sequence 1: NP_001369036.1
• Gene: Hipk / 38070
• FlyBaseID: FBgn0035142
• Length: 1409
• Species: Drosophila melanogaster
• Sequence 2: NP_031738.2
• Gene: Clk2 / 12748
• MGIID: 1098669
• Length: 499
• Species: Mus musculus
• Alignment Length: 391
• Identity: 120/391 - (30%)
• Similarity: 192/391 - (49%)
• Gaps: 71/391 - (18%)

  Fly   156 SGGHANTQPPSKRSSS-GADGDYQLVQHEVLYSLSAEYEVLEFLGRGTFGQVVKC--WKRGTSEI 217
            |..|:     |:|:.| ..|.:..|:.| |...|...||::..||.||||:||:|  .:||.::
Mouse   131 SSSHS-----SRRAKSVEDDAEGHLIYH-VGDWLQERYEIVSTLGEGTFGRVVQCVDHRRGGTQ- 188

  Fly   218 VAIKILKNHPSYARQGQIEVSILSRLSQENADEFNF-VRAFECFQHKNHTCLVFEMLEQNLYDFL 281
            ||:||:||...|....::|:::|.::::::.|..|. |:.|:.|.:..|.|:.||:|..:.:|||
Mouse   189 VALKIIKNVEKYKEAARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGHMCISFELLGLSTFDFL 253

  Fly   282 KQNKFSPLPLKYIRPILEQVLTALLKLKQLGLIHADLKPENIMLVDPVRQPYR------------ 334
            |.|.:.|.|:..:|.:..|:..|:..|....|.|.|||||||:.|:   ..|.
Mouse   254 KDNNYLPYPIHQVRHMAFQLCQAVKFLHDNKLTHTDLKPENILFVN---SDYELTYNLEKKRDER 315

  Fly   335 ------VKVIDFGSAS----HVSKTVCNTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVVAELFL 389
                  |:|:|||||:    |.|     |.:.:|:|||||:||.|.:.:..|:||:||::.|.::
Mouse   316 SVKSTAVRVVDFGSATFDHEHHS-----TIVSTRHYRAPEVILELGWSQPCDVWSIGCIIFEYYV 375

  Fly   390 GWPLYPGSSEFDQIRYISQTQGLPTEHMLNSASKTSKFFYRD-VDSTYPFWRLKTTEEHEAETNT 453
            |:.|:......:.:..:.:..|.....|:....| .|:|||. :|     |...|:.......|
Mouse   376 GFTLFQTHDNREHLAMMERILGPVPSRMIRKTRK-QKYFYRGRLD-----WDENTSAGRYVREN- 433

  Fly   454 KSKEARKYIFNCLDDIGQVNVPTDLEGGQLLAEKTDRREFIDLLKRMLTIDQERRLTPAEALNHS 518
             .|..|:|                     |.:|..|..:..||::.||..:..:|||..|||.|.
Mouse   434 -CKPLRRY---------------------LTSEAEDHHQLFDLIENMLEYEPAKRLTLGEALQHP 476

  Fly   519 F 519
            |
Mouse   477 F 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hipk	NP_001369036.1	STKc_HIPK	192..520	CDD:271113	110/354 (31%)
		PHA03378	<1080..1327	CDD:223065
Clk2	NP_031738.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..142		4/15 (27%)
		PKc_CLK2	149..478	CDD:271117	114/368 (31%)
		S_TKc	162..478	CDD:214567	110/354 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810