DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and Ppig

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_113981.2	Gene:	Ppig / 83624	RGDID:	620315	Length:	752	Species:	Rattus norvegicus

Alignment Length:	165	Identity:	73/165 - (44%)
Similarity:	96/165 - (58%)	Gaps:	20/165 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GEITVELYWKHAPNTCRNFAEL--SRRG---------YYNNVVFHRIIRDFMIQGGD-PTGTGRG 82
            |.:..||:....|.||.||..|  ..:|         :|.:.:|||:::|||:|||| ..|.|||
  Rat    22 GRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRG 86

  Fly    83 GASIYGSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEV 147
            |.||||..|.||... ::|....:|||||.|.||||||||||..||..|||.|.:||:|.:|.||
  Rat    87 GESIYGGFFEDESFA-VKHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEV 150

  Fly   148 VKRIGMVETDKNDRPVDPLRII-------KAKVEK 175
            |:.|...:||...:|...:||:       |:||:|
  Rat   151 VREIENQKTDAASKPFAEVRILSCGELVPKSKVKK 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	69/158 (44%)
Ppig	NP_113981.2	cyclophilin	8..175	CDD:412213	69/153 (45%)
Ppig	NP_113981.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..752		3/4 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.900