DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and Cwc27

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_001347023.1	Gene:	Cwc27 / 67285	MGIID:	1914535	Length:	472	Species:	Mus musculus

Alignment Length:	153	Identity:	77/153 - (50%)
Similarity:	101/153 - (66%)	Gaps:	3/153 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VTLETSMGEITVELYWKHAPNTCRNFAELSRRGYYNNVVFHRIIRDFMIQGGDPTGTGRGGASIY 87
            |.|:|:.|:|.:||:.|.||..||||.:|....||:|.:|||::..|::|||||||||.||.|||
Mouse    15 VLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGTGGESIY 79

  Fly    88 GSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVVKRIG 152
            |:.|.||.|..||....|:::|||:||..||||||.||.....|:.||||||:| ||..|...:.
Mouse    80 GAPFKDEFHSRLRFNRRGLVAMANAGPHDNGSQFFFTLGRADELNNKHTIFGKV-TGDTVYNMLR 143

  Fly   153 MVETDKND--RPVDPLRIIKAKV 173
            :.|.|.:|  ||.:|.||...:|
Mouse   144 LTEVDIDDEERPRNPHRIKSCEV 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	75/147 (51%)
Cwc27	NP_001347023.1	cyclophilin_CeCYP16-like	8..178	CDD:238906	77/153 (50%)
Cwc27	NP_001347023.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	431..472
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910