Protein Alignment Cypl and RANBP2

DIOPT Version :10

• Sequence 1: NP_523874.1
• Gene: Cypl / 38069
• FlyBaseID: FBgn0035141
• Length: 176
• Species: Drosophila melanogaster
• Sequence 2: XP_005264059.1
• Gene: RANBP2 / 5903
• HGNCID: 9848
• Length: 3258
• Species: Homo sapiens
• Alignment Length: 127
• Identity: 64/127 - (50%)
• Similarity: 83/127 - (65%)
• Gaps: 5/127 - (3%)

  Fly    29 MGEITVELYWKHAPNTCRNFAEL--SRRGY-YNNVVFHRIIRDFMIQGGDPT-GTGRGGASIYGS 89
            :|.||:||:....|.|..||..|  ..:|: :.|.:|||:|.||:.||||.| ..|.||.||||.
Human  3111 LGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDFVCQGGDITKHDGTGGQSIYGD 3175

  Fly    90 EFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVVKRI 151
            :|.|| :.|::|||.|:|||||.|.:||.|||.|||...:.||.||.:||.|..||:.||:|
Human  3176 KFEDE-NFDVKHTGPGLLSMANQGQNTNNSQFVITLKKAEHLDFKHVVFGFVKDGMDTVKKI 3236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:469651	64/127 (50%)
RANBP2	XP_005264059.1	LapB	<33..222	CDD:442196
		TPR repeat	59..89	CDD:276809
		TPR repeat	94..123	CDD:276809
		RanBD1_RanBP2-like	1186..1302	CDD:270203
		zf-RanBP	1351..1381	CDD:395516
		RanBP2-type Zn finger	1355..1375	CDD:275375
		zf-RanBP	1415..1443	CDD:395516
		RanBP2-type Zn finger	1419..1438	CDD:275375
		zf-RanBP	1479..1508	CDD:395516
		RanBP2-type Zn finger	1483..1502	CDD:275375
		zf-RanBP	1543..1572	CDD:395516
		RanBP2-type Zn finger	1547..1566	CDD:275375
		zf-RanBP	1606..1635	CDD:395516
		RanBP2-type Zn finger	1610..1629	CDD:275375
		zf-RanBP	1665..1694	CDD:395516
		RanBP2-type Zn finger	1669..1688	CDD:275375
		zf-RanBP	1724..1753	CDD:395516
		RanBP2-type Zn finger	1728..1747	CDD:275375
		zf-RanBP	1781..1809	CDD:395516
		RanBP2-type Zn finger	1785..1804	CDD:275375
		RanBD2_RanBP2-like	2027..2143	CDD:269998
		RanBD3_RanBP2-like	2324..2440	CDD:270204
		IR1-M	2657..2719	CDD:463488
		IR1-M	2735..2791	CDD:463488
		RanBD4_RanBP2-like	2959..3075	CDD:269999
		cyclophilin_ABH_like	3098..3256	CDD:238907	64/127 (50%)