DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and ppid

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_001002065.1	Gene:	ppid / 415155	ZFINID:	ZDB-GENE-040625-34	Length:	371	Species:	Danio rerio

Alignment Length:	179	Identity:	79/179 - (44%)
Similarity:	97/179 - (54%)	Gaps:	20/179 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PDKAWQPH-FVTLETS---MGEITVELYWKHAPNTCRNFAEL--SRRG---------YYNNVVFH 63
            |..|..|. |..:|..   :|.:..||:....|.|..||..|  ..:|         ::....||
Zfish    10 PGNAENPRVFFDVEIGAERVGRVVFELFADVVPKTAENFRALCTGEKGVGKSTGKPLHFKGCPFH 74

  Fly    64 RIIRDFMIQGGD-PTGTGRGGASIYGSEFADE-LHGDLRHTGAGILSMANSGPDTNGSQFFITLA 126
            |||:.||||||| ....|.||.||||.:|.|| .|  .:|...|:|||||:||:|||||||||..
Zfish    75 RIIKSFMIQGGDFSNQNGTGGESIYGDKFEDENFH--YKHDREGLLSMANAGPNTNGSQFFITTV 137

  Fly   127 PTQWLDGKHTIFGRVYTGMEVVKRIGMVETDKNDRPVDPLRIIKAKVEK 175
            ||..|||||.:||:|..||.|||.:..:|| |.|.||.|..|.:....|
Zfish   138 PTPHLDGKHVVFGQVLKGMGVVKMLEAMET-KEDNPVKPCVIAECGEHK 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	74/161 (46%)
ppid	NP_001002065.1	cyclophilin_ABH_like	16..182	CDD:238907	76/168 (45%)
		TPR_11	223..304	CDD:290150
		TPR repeat	223..268	CDD:276809
		TPR_12	271..340	CDD:290160
		TPR repeat	273..303	CDD:276809
		TPR repeat	308..336	CDD:276809
		TPR_1	309..341	CDD:278916
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.900