DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cypl and CG8336

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	60/170 - (35%)
Similarity:	87/170 - (51%)	Gaps:	20/170 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KAWQPHFVTLETSMGE-----ITVELYWKHAPNTCRNF----------AELSRRGYYNNVVFHRI 65
            |:..| .|.|:.|:|:     :.:||.....|.|..||          ..|.:..:|....||:|
  Fly    11 KSTNP-LVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKI 74

  Fly    66 IRDFMIQGGDPT-GTGRGGASIYGSEFADELHGDLRHTGAGILSMANSG-PDTNGSQFFITLAPT 128
            .|.|::|.||.. ..|..|.||||..|.|| :.:|.|...|::||||.| |::|.|||||:.|..
  Fly    75 KRVFVVQSGDVVKNDGSSGESIYGPVFDDE-NFELSHNEEGVVSMANYGKPNSNNSQFFISAAGC 138

  Fly   129 QWLDGKHTIFGRVYTGMEVVKRIGMVETDKNDRPVDPLRI 168
            :.|:|.:.:.|||..|:.:|..:....||:.| |..|:.|
  Fly   139 ENLNGTNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVI 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	57/162 (35%)
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	59/166 (36%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447175
Domainoid	1	1.000	81	1.000	Domainoid score	I449
eggNOG	1	0.900	-	-		E1_COG0652
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740