DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and Ppib

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_035279.2	Gene:	Ppib / 19035	MGIID:	97750	Length:	216	Species:	Mus musculus

Alignment Length:	157	Identity:	78/157 - (49%)
Similarity:	103/157 - (65%)	Gaps:	8/157 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ETSMGEITVELYWKHAPNTCRNFAELS--RRGY-YNNVVFHRIIRDFMIQGGDPT-GTGRGGASI 86
            :.|:|.:...|:.|..|.|..||..|:  .:|: |.|..|||:|:||||||||.| |.|.||.||
Mouse    54 DESVGRVVFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSI 118

  Fly    87 YGSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVVKRI 151
            ||..|.|| :..|:|.|.|.:||||:|.||||||||||...|.||||||.:||:|..||:||:::
Mouse   119 YGERFPDE-NFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTSWLDGKHVVFGKVLEGMDVVRKV 182

  Fly   152 GMVETDKNDRPVDPLRII---KAKVEK 175
            ...:||..|:|:..:.|:   |.:|||
Mouse   183 ESTKTDSRDKPLKDVIIVDSGKIEVEK 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	74/150 (49%)
Ppib	NP_035279.2	cyclophilin_ABH_like	45..203	CDD:238907	74/149 (50%)
Ppib	NP_035279.2	Prevents secretion from ER. /evidence=ECO:0000250	213..216
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810