DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cypl and cyn-8

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_509507.1	Gene:	cyn-8 / 181136	WormBaseID:	WBGene00000884	Length:	447	Species:	Caenorhabditis elegans

Alignment Length:	156	Identity:	78/156 - (50%)
Similarity:	89/156 - (57%)	Gaps:	20/156 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GEITVELYWKH-APNTCRNF-----AELSR-RGY---YNNVVFHRIIRDFMIQGGDPT-GTGRGG 83
            |.|...| |.| .|.|..||     .||.: .|:   |...||||:|:.|||||||.| |.|.||
Worm    23 GRIVFSL-WNHCCPRTVENFRAFCTGELGKMNGHYASYQGSVFHRVIKGFMIQGGDITHGNGTGG 86

  Fly    84 ASIYGSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVV 148
            .||||..|.|| :..|:|....:|||||.||||||||||||......|||||.:||.|..|:|||
Worm    87 YSIYGRTFDDE-NLALKHKKPYLLSMANRGPDTNGSQFFITSEEVPHLDGKHCVFGEVIKGVEVV 150

  Fly   149 KRIGMVETDKNDRPVDPLRIIKAKVE 174
            |.|..:||...|:||       .|||
Worm   151 KAIENLETGNEDKPV-------CKVE 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	75/150 (50%)
cyn-8	NP_509507.1	cyclophilin	10..174	CDD:412213	78/156 (50%)
cyn-8	NP_509507.1	ATP-synt_Fo_b	<324..391	CDD:349951
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910