DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and Nktr

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	XP_030099969.1	Gene:	Nktr / 18087	MGIID:	97346	Length:	1556	Species:	Mus musculus

Alignment Length:	179	Identity:	75/179 - (41%)
Similarity:	101/179 - (56%)	Gaps:	18/179 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 AGGIPDKAWQPHFVTLETS---MGEITVELYWKHAPNTCRNFAEL-----------SRRGYYNNV 60
            |.|..|:. |.|| .:|.:   :|.|..:|:....|.||:||..|           .::..|...
Mouse   102 AMGAQDRP-QCHF-DIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGS 164

  Fly    61 VFHRIIRDFMIQGGD-PTGTGRGGASIYGSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFIT 124
            .|||::::||||||| ..|.|:||.||||..|.|| :..|:|..|.:|||||.|..|||||||||
Mouse   165 TFHRVVKNFMIQGGDFSEGNGKGGESIYGGYFKDE-NFILKHDRAFLLSMANRGKHTNGSQFFIT 228

  Fly   125 LAPTQWLDGKHTIFGRVYTGMEVVKRIGMVETDKNDRPVDPLRIIKAKV 173
            ..|...|||.|.:||.|.:|.||:::|..::||...||...:|:|...|
Mouse   229 TKPAPHLDGVHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGV 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	67/160 (42%)
Nktr	XP_030099969.1	cyclophilin	109..276	CDD:381853	71/169 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900