DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and cyn-15

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_493378.1	Gene:	cyn-15 / 173225	WormBaseID:	WBGene00000891	Length:	629	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	77/152 - (50%)
Similarity:	103/152 - (67%)	Gaps:	2/152 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LETSMGEITVELYWKHAPNTCRNFAELSRRGYYNNVVFHRIIRDFMIQGGDPTGTGRGGASIYGS 89
            :.||.|:||:.|:....|.|..||...|||||||.:.|||:|:.||||.|||:|.|.||.||:|.
Worm   478 IHTSFGDITIRLFGDECPKTVENFCTHSRRGYYNGLTFHRVIKSFMIQTGDPSGKGTGGESIWGE 542

  Fly    90 EFADELHGDLRHTGAGILSMANS-GPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVVKRIGM 153
            :|.||.|..|||.....:||||: |.:|||||||||:.|..|||||:|:||.|..||.||:||..
Worm   543 DFEDEFHPRLRHDKPFKVSMANAGGGNTNGSQFFITVCPADWLDGKNTLFGEVTAGMSVVQRINQ 607

  Fly   154 VET-DKNDRPVDPLRIIKAKVE 174
            |.| :::.||.:.::|:...::
Worm   608 VSTFERSGRPRESIQIMSISLK 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	77/146 (53%)
cyn-15	NP_493378.1	WD40	53..>285	CDD:392136
		WD40 repeat	101..142	CDD:293791
		WD40 repeat	150..185	CDD:293791
		WD40 repeat	192..237	CDD:293791
		cyclophilin	477..626	CDD:381853	77/147 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920