DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and Ppif

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_598845.1	Gene:	Ppif / 105675	MGIID:	2145814	Length:	206	Species:	Mus musculus

Alignment Length:	153	Identity:	71/153 - (46%)
Similarity:	88/153 - (57%)	Gaps:	17/153 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NNAGGIPDKAWQPHFVTLETS-----MGEITVELYWKHAPNTCRNFAEL--SRRGY-YNNVVFHR 64
            |::.|.|       .|.|:..     :|.:.:||.....|.|..||..|  ..:|: |....|||
Mouse    39 NSSSGNP-------LVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHR 96

  Fly    65 IIRDFMIQGGDPTG-TGRGGASIYGSEFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPT 128
            :|..||.|.||.|. .|.||.|||||.|.|| :..|:|.|.|:|||||:||:||||||||....|
Mouse    97 VIPAFMCQAGDFTNHNGTGGRSIYGSRFPDE-NFTLKHVGPGVLSMANAGPNTNGSQFFICTIKT 160

  Fly   129 QWLDGKHTIFGRVYTGMEVVKRI 151
            .||||||.:||.|..||:|||:|
Mouse   161 DWLDGKHVVFGHVKEGMDVVKKI 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	67/137 (49%)
Ppif	NP_598845.1	cyclophilin_ABH_like	45..203	CDD:238907	69/147 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900