DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cypl and ppwd1

DIOPT Version :9

Sequence 1:	NP_523874.1	Gene:	Cypl / 38069	FlyBaseID:	FBgn0035141	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	XP_002934239.3	Gene:	ppwd1 / 100488042	XenbaseID:	XB-GENE-1001509	Length:	640	Species:	Xenopus tropicalis

Alignment Length:	151	Identity:	85/151 - (56%)
Similarity:	104/151 - (68%)	Gaps:	1/151 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LETSMGEITVELYWKHAPNTCRNFAELSRRGYYNNVVFHRIIRDFMIQGGDPTGTGRGGASIYGS 89
            :.||||:|.|:|:....|.|..||...||.||||..:|||:|:.||||.|||||||.||.||:|.
Frog   490 IHTSMGDIHVKLFPVECPKTVENFCVHSRNGYYNRHMFHRVIKGFMIQTGDPTGTGMGGESIWGG 554

  Fly    90 EFADELHGDLRHTGAGILSMANSGPDTNGSQFFITLAPTQWLDGKHTIFGRVYTGMEVVKRIGMV 154
            ||.||.|..|||.....|||||:||.|||||||:|:.||.|||.|||:||||..|||||:||...
Frog   555 EFEDEFHATLRHDRPYTLSMANAGPSTNGSQFFLTVVPTPWLDNKHTVFGRVTKGMEVVQRICNS 619

  Fly   155 ETD-KNDRPVDPLRIIKAKVE 174
            :.: |.|:|.:.:.||...|:
Frog   620 KVNPKTDKPYEDISIINITVK 640

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cypl	NP_523874.1	cyclophilin	24..170	CDD:294131	83/145 (57%)
ppwd1	XP_002934239.3	WD40	83..312	CDD:421866
		WD40 repeat	88..125	CDD:293791
		WD40 repeat	131..169	CDD:293791
		WD40 repeat	177..213	CDD:293791
		WD40 repeat	221..266	CDD:293791
		cyclophilin_WD40	489..637	CDD:238908	84/146 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920