DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BORCS6 and BORCS6

DIOPT Version :9

Sequence 1:	NP_001261214.1	Gene:	BORCS6 / 38068	FlyBaseID:	FBgn0035140	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_060092.2	Gene:	BORCS6 / 54785	HGNCID:	25939	Length:	357	Species:	Homo sapiens

Alignment Length:	328	Identity:	82/328 - (25%)
Similarity:	141/328 - (42%)	Gaps:	83/328 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RPRYGYVAEESGPSEGAARSSGS--GATPASSYTEIPFLAQYPGAVPEHVLQDLTPTATGHAAIP 73
            ||....:..|.|| :|....:||  ||               |||  ||     .|:.:.....|
Human    72 RPEREALENEPGP-QGTLSGAGSRRGA---------------PGA--EH-----EPSLSSRHKNP 113

  Fly    74 GSTKTRPNGEKYLNLDSGED-------------PDEEDDPLEE---------------EDNSNSN 110
            ...:.:|:        ||.|             ..||:|..||               :|:.:.:
Human   114 APPEGKPS--------SGRDCRRGGPGGGMDVEQQEEEDNDEEAAAGSRAGRSFSSRLQDSRSLD 170

  Fly   111 SNSK-----GSSGDIERHR---LKAESTVPYELDGETSDSDGMRHFVAHDLEAKLRERVAASAYS 167
            ..|:     ||||..|...   .:|..:.|.||:|..|....:.||||::|:.|:|...|.....
Human   171 GLSEACGGAGSSGSAESGAGGGRRATISSPLELEGTVSRHGDLTHFVANNLQLKIRLSGAPPPPP 235

  Fly   168 SEHTTPLSSMGPIGATSGNGLLTRRFLQSRNIPEVDGSVLSDIELEAQYLASSVDNLMENLGNLL 232
            |....|..:..|....:              ||.:|..||.|:|..::.|...||.|:..||..:
Human   236 SAPARPCPAPAPTPTPA--------------IPPIDPEVLRDLERLSRELGGRVDRLLRGLGGAV 286

  Fly   233 HSISSITADNVEVHRNAVNKLTDTLDANIKCQYQLLAKAEEITKSMKPTEQLGQRIRQIKRLVDM 297
            ..:::::...::.:|:||:.|.:.:|.:||..|.|||:.||:.::::|.:.|.:::|.|:|.:::
Human   287 QELTALSVGCIQTYRDAVDSLGEAVDMSIKGMYTLLARCEELERALQPVQGLARQVRDIRRTLEV 351

  Fly   298 LDS 300
            |::
Human   352 LEA 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BORCS6	NP_001261214.1	DUF2365	142..301	CDD:287166	43/159 (27%)
BORCS6	NP_060092.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	20..196		35/161 (22%)
		DUF2365	210..355	CDD:287166	39/144 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	227..256		3/28 (11%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158451
Domainoid	1	1.000	81	1.000	Domainoid score	I8575
eggNOG	1	0.900	-	-		E1_KOG4514
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I5113
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006641
OrthoInspector	1	1.000	-	-		oto90394
orthoMCL	1	0.900	-	-		OOG6_106297
Panther	1	1.100	-	-	LDO	PTHR13440
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4339
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.820