Protein Alignment trh and arnt

DIOPT Version :10

• Sequence 1: NP_001261207.1
• Gene: trh / 38065
• FlyBaseID: FBgn0262139
• Length: 1022
• Species: Drosophila melanogaster
• Sequence 2: NP_001428910.1
• Gene: arnt / 493634
• ZFINID: ZDB-GENE-060126-7
• Length: 747
• Species: Danio rerio
• Alignment Length: 911
• Identity: 186/911 - (20%)
• Similarity: 306/911 - (33%)
• Gaps: 281/911 - (30%)

  Fly    88 KEKSRDAARSRRGKENYEFYELAKMLPLPAAITSQLDKASIIRLTISYLKLRDFSGHGDPPWTRE 152
            :|...:..|.||.|......||:.|:|..:|:..:.||.:|:|:.:|::|....:|:.....|.:
Zfish    65 RENHSEIERRRRNKMTAYITELSDMVPACSALARKPDKLTILRMAVSHMKSLRGTGNTSTDGTYK 129

  Fly   153 ASSSSKLKSAAIRRSPAVDLFEQHQGTHILQSLDGFALAVAAD-GRFLYISETVSIYLGLSQVEM 216
            .|.                |.:|.....||::.|||...|:.: ||.:|:|::|:..|..:|.:.
Zfish   130 PSF----------------LTDQELKHLILEAADGFLFVVSCETGRVVYVSDSVTPVLNQAQSDW 178

  Fly   217 TGSSIFDYIHQADHSEIADQLGLSLTSGGGGGGGSSSSGGGGGGAGGGMASPTSGASDDGSGTHG 281
            .|||::|.:|..|..::.:|  ||.|......|.......|.....||.|:
Zfish   179 LGSSLYDQLHPDDVEKLREQ--LSTTENNNNSGRMLDMKTGTVKKEGGQAT-------------- 227

  Fly   282 TNNPDVAASMTQASTSGYKGYDRSFCVRMK-----------------STLTKRG----------- 318
                 |..||         |..|||..||:                 .|..:.|
Zfish   228 -----VRMSM---------GARRSFICRMRCGVCPVEPVSLNRLNFLRTRNRNGLGSAKDGEQQY 278

  Fly   319 ----CHFKSSGYRASDATSNCNNGNNASNNAKNVKNPGSNYSVVLLLCKLRPQYTFSHSRKSQPP 379
                |    :||..|...:..|.....::|     |.|:.:.:|
Zfish   279 VVVHC----TGYIRSWPPAGMNLSEEEADN-----NQGNRFCLV--------------------- 313

  Fly   380 LLGMVALAIALPPPSVHEIRLECDMFVTRVNFDLRVAHCEPRVSDLLDYSPEDLVNKSLYSLCHA 444
            .:|.:.:.......|::.|.:..: |::|.|........:.|.:..:.:..::|:.|::....|.
Zfish   314 AIGRLQVTCCPSDTSINNISVPVE-FISRHNSQGVYTFVDHRCTATVGFQTQELLGKNILDFAHP 377

  Fly   445 EDANRLRKSHSDLIE-KGQVLTGYYRLMNKSGGYTWLQTCATVVCSTKNADEQNIICVNYVISNR 508
            ||...||.|...::: :|||::..:|..:||..:.|::|.:....:..:.:.:.|||.|..: ||
Zfish   378 EDQGLLRDSLQQVVKLRGQVMSVMFRFQSKSREWVWMRTSSFTFQNPFSEEIEYIICTNTNV-NR 441

  Fly   509 ENENMILDCCQLEPSPDSIKHEEGLGNDKSSGSPGGDASGEGNSHLSAGDMKLNSPKTDSEGHSH 573
                                     |:.:.|.||                  |:||
Zfish   442 -------------------------GSSEGSVSP------------------LSSP--------- 454

  Fly   574 RGRGRSAAASHGSSMNSLTMIKDSPTPLGVEIDSGVLPTTVATPVPAATPPVQSTKRKRKTKASQ 638
                     |.|.|                       |...:||.|......|..:::.:.....
Zfish   455 ---------SLGQS-----------------------PNCPSTPSPGCVTVRQLQQQQVELDGGG 487

  Fly   639 HAEDQGQEQVISEQPLPKLPTMEQRDQQPRSRLPSIVD-EQPSSAADSAVKDLEQAMSKHLPSPA 702
            .:::...|.  |:..||::..          :...:|. :..|.|..|:|...:|.    .|..|
Zfish   488 MSQETPYEN--SQVALPQVSV----------QTCGVVSADHSSKAVSSSVSSGQQV----YPPAA 536

  Fly   703 AVVSVAPPNTDFSADSLLKQQQQQQQLDPNEKSSTIQWIGTPYQQPPAPMPATALLRQLYANRES 767
            |..|.|.|...|.:..|                        |.|..|....|..:|.|:  :|:|
Zfish   537 AFPSPARPTETFRSPVL------------------------PQQMVPVAHSAGQMLAQM--SRQS 575

  Fly   768 VIRATARQTPTGVGPGVFYGDQQTGPL--PTPPGSESSYENQYLQLHSAASGGHPGGQKTSADAF 830
                    ||:||      ......|:  |:.|.:.....|...|..|......|.|:..||.
Zfish   576 --------TPSGV------SGSNNSPIQAPSGPTAPPGLWNTTRQPFSTQQVAGPIGKNQSAP-- 624

  Fly   831 TNLVSTYGGYHSSIDYHNAMTPPSSVSPRDSNQPGKAAPVLASNGGYDYA---PDPLRGQYATSS 892
                ...||:.|      |..|.:|.|   ..|.|.|:..:||...|...   .:|....|
Zfish   625 ----FNMGGFSS------ASAPSTSSS---FGQMGGASASMASTSSYQQINSHSNPSTNGY---- 672

  Fly   893 GDV--VPATLPLKPQASYTATMH-PSGSTTTEGGVTYSNLDQPQYFAPHSSFHLYHKGSPASGWY 954
            |||  :.|....:|....|.... ||.:.|.....|....:|...| |.....|...||.::|.:
Zfish   673 GDVGQIAAAFGTRPAEGVTGWQQWPSQTHTQASADTQVQNNQTDMF-PDVLSMLDQSGSFSNGDF 736

  Fly   955 S 955
            |
Zfish   737 S 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
trh	NP_001261207.1	bHLH-PAS_trachealess_like	83..152	CDD:381576	18/63 (29%)
		PAS	176..236	CDD:214512	19/60 (32%)
		PAS_3	415..502	CDD:430001	20/87 (23%)
arnt	NP_001428910.1	None