DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1233 and CG11456

DIOPT Version :9

Sequence 1:	NP_612034.1	Gene:	CG1233 / 38063	FlyBaseID:	FBgn0035137	Length:	1129	Species:	Drosophila melanogaster
Sequence 2:	NP_001262130.1	Gene:	CG11456 / 40309	FlyBaseID:	FBgn0037031	Length:	445	Species:	Drosophila melanogaster

Alignment Length:	414	Identity:	99/414 - (23%)
Similarity:	160/414 - (38%)	Gaps:	108/414 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   683 NAEEGTAAGGRGTVPPLVPVTSSEGTASVAQSAALGSLPVPPLVPLAAEMNAAIEKPARIYVANN 747
            :.:|.||||           ::|:...:|.:.:.....|...|.|:..       |..|:.:..|
  Fly    50 STKEQTAAG-----------SNSQDKQTVVERSENSEPPASELQPMPF-------KDFRLVLRAN 96

  Fly   748 LLPAAVDPPLLGGGTSVRGRPYGAKHSGGAASKRKLSLGPNQVPEGGKCLVEGCMFRFKSPVTLE 812
            :|    :|...|                                       :.|.|:|:....:|
  Fly    97 ML----EPCSFG---------------------------------------KECPFKFQDATKME 118

  Fly   813 YHGRCHNGSLSSNQPVVCPECKSSNFSNWNCLHTHLWRTHQIDMELYSCQL--CSFKTPIYSRLV 875
            .|..||.|...|     |.|| .....||.....|||:.||:|::|..|.:  |::|:|| |.||
  Fly   119 LHCSCHKGGSFS-----CCEC-GMELPNWRRCSAHLWKAHQVDVDLLVCPVFECNYKSPI-SALV 176

  Fly   876 NTHAKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLGMGKQSNEQISVGPEGNPVVMHR-- 938
            ..|.::|.:.|       .:..::...::..|:|         |:.:.:::..|...|....:
  Fly   177 WRHMQVHKKWR-------PRVLRSLAAVQRRRKL---------KEQSAEMAAQPAALPPSSKKNK 225

  Fly   939 ------CEDCGAAFKQKKTLREHLCKERN--EQLECPECQRRFGSKSSLRLHLRSHQEHKRFRCD 995
                  ||.|...|...|||.:|:....|  :...|..|.::...|:||.:|:|.|...|..:|.
  Fly   226 YYAEKTCEICNRKFVNGKTLSKHVKTVHNKIKPFICNVCGKKTARKASLIIHMRQHTGEKPLQCG 290

  Fly   996 TCDHETSDHNAYRRHLATHKESKRYS---CPHCDFRAIQSTAFRIHLQTRHPEQELSTIIYK--- 1054
            .|...|.|.:...:|...|......|   |..||:..||:.|.:.|::..|.|      .|:
  Fly   291 ECKFSTRDPSVLHKHRQRHDSQDTRSSLKCSQCDYFCIQANALKRHMRLNHAE------AYRDLC 349

  Fly  1055 CNQCNFTSINQGLLQVHQAKHDAG 1078
            |:.|:|||||...|:.|:..|..|
  Fly   350 CDICSFTSINVERLRAHKQDHRQG 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1233	NP_612034.1	C2H2 Zn finger	830..852	CDD:275368	8/21 (38%)
		C2H2 Zn finger	861..882	CDD:275368	9/22 (41%)
		zf-H2C2_2	875..899	CDD:290200	4/23 (17%)
		zf-C2H2	888..910	CDD:278523	1/21 (5%)
		C2H2 Zn finger	890..910	CDD:275368	1/19 (5%)
		zf-C2H2_2	893..999	CDD:289522	25/115 (22%)
		C2H2 Zn finger	939..956	CDD:275368	7/16 (44%)
		RPB9	966..1061	CDD:224510	28/100 (28%)
		C2H2 Zn finger	966..986	CDD:275368	7/19 (37%)
		C2H2 Zn finger	994..1014	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1022..1042	CDD:275368	7/19 (37%)
		C2H2 Zn finger	1055..1075	CDD:275368	9/19 (47%)
CG11456	NP_001262130.1	C2H2 Zn finger	232..253	CDD:275368	8/20 (40%)
		C2H2 Zn finger	261..281	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..309	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24408
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010