DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1233 and znf423

DIOPT Version :9

Sequence 1:	NP_612034.1	Gene:	CG1233 / 38063	FlyBaseID:	FBgn0035137	Length:	1129	Species:	Drosophila melanogaster
Sequence 2:	XP_002937417.2	Gene:	znf423 / 100491000	XenbaseID:	XB-GENE-490169	Length:	1289	Species:	Xenopus tropicalis

Alignment Length:	421	Identity:	94/421 - (22%)
Similarity:	144/421 - (34%)	Gaps:	135/421 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   792 EGGKCLVEGCMFRFKSPVTLEY---HGRCHNGSLSSNQPVVCPECKSSNFSNWNCLHTHLWRTHQ 853
            |||..|...|.|..||...|.|   |.:.|:..|    |..|..| |..|.:......|: :.|.
Frog   133 EGGSGLPYPCQFCDKSFSRLSYLKRHEQIHSDKL----PFKCTYC-SRLFKHKRSRDRHI-KLHT 191

  Fly   854 IDMELYSCQLCSFKTPIYSRL--VNTHAKIHSEERNYKCEQCGKGFKNTKQLKNHRRLHRTQGLG 916
            .|.: |.|..|.   ..:||.  :..|.|.||..:.:||..|.:||.:|..|::|.:.||.....
Frog   192 GDKK-YHCHECE---AAFSRSDHLKIHLKTHSSSKPFKCTVCKRGFSSTSSLQSHMQAHRKNKEY 252

  Fly   917 MGKQSNEQISVGPEGNPVVMHR----CEDCGAAFKQKKTLREHLCKERNE-----QLECPECQRR 972
            |.|...|            |.:    |:.|...|.|.:.|.:|:.....:     .|:|..|...
Frog   253 MTKSDRE------------MKKDDFMCDYCEETFSQTEDLEKHVMTRHPQLSEKADLQCIHCPEV 305

  Fly   973 FGSKSSLRLHLRSHQEHKRFRCDTCDHETSDHNAYRRHLATH----------------------- 1014
            |..::||..|:.....:|:.:|..|..:.|.......||.:|
Frog   306 FADETSLLTHIDHVHANKKHKCPMCPEQFSSVEEVYCHLDSHRQPDSSNHSISPDPVLGSVASMS 370

  Fly  1015 ---------------------------------KESKR------YSCPHCDFRAIQSTA-FRIHL 1039
                                             :|.:|      ||||:|..|...|.| ..|||
Frog   371 SATPDSSASLERASTPDSTLKPIRGHKRTGSFDREDERNWPKITYSCPYCSKRDFNSLAVLEIHL 435

  Fly  1040 QTRH---PEQELSTIIYKCNQC-----NFTSINQGLLQVHQAKHDAGNHNQTLASSQGDVPVEKQ 1096
            :|.|   |:|.     :.|..|     ...::|:.:.:||:      ||...:...
Frog   436 KTIHVDKPQQN-----HTCQICLDSLPTLYNLNEHVRKVHK------NHAYPMVQF--------- 480

  Fly  1097 SQIKVESNLVLAHSS--TKVATEVIKAQENI 1125
                  ||:...|.:  .::..::...||:|
Frog   481 ------SNITAFHCNYCPEMFADINSLQEHI 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1233	NP_612034.1	C2H2 Zn finger	830..852	CDD:275368	5/21 (24%)
		C2H2 Zn finger	861..882	CDD:275368	6/22 (27%)
		zf-H2C2_2	875..899	CDD:290200	9/23 (39%)
		zf-C2H2	888..910	CDD:278523	8/21 (38%)
		C2H2 Zn finger	890..910	CDD:275368	7/19 (37%)
		zf-C2H2_2	893..999	CDD:289522	28/114 (25%)
		C2H2 Zn finger	939..956	CDD:275368	5/16 (31%)
		RPB9	966..1061	CDD:224510	32/165 (19%)
		C2H2 Zn finger	966..986	CDD:275368	6/19 (32%)
		C2H2 Zn finger	994..1014	CDD:275368	5/19 (26%)
		C2H2 Zn finger	1022..1042	CDD:275368	9/20 (45%)
		C2H2 Zn finger	1055..1075	CDD:275368	5/24 (21%)
znf423	XP_002937417.2	COG5048	<141..246	CDD:227381	34/114 (30%)
		C2H2 Zn finger	142..162	CDD:275368	7/19 (37%)
		C2H2 Zn finger	170..190	CDD:275368	5/21 (24%)
		COG5048	196..601	CDD:227381	73/351 (21%)
		C2H2 Zn finger	198..218	CDD:275368	6/22 (27%)
		C2H2 Zn finger	226..246	CDD:275368	7/19 (37%)
		C2H2 Zn finger	267..286	CDD:275368	6/18 (33%)
		C2H2 Zn finger	299..316	CDD:275368	5/16 (31%)
		C2H2 Zn finger	417..438	CDD:275368	9/20 (45%)
		C2H2 Zn finger	449..470	CDD:275368	3/20 (15%)
		C2H2 Zn finger	488..509	CDD:275368	3/18 (17%)
		C2H2 Zn finger	525..546	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		C2H2 Zn finger	670..690	CDD:275368
		C2H2 Zn finger	700..717	CDD:275368
		C2H2 Zn finger	728..749	CDD:275368
		C2H2 Zn finger	758..779	CDD:275368
		C2H2 Zn finger	789..809	CDD:275368
		C2H2 Zn finger	815..833	CDD:275368
		C2H2 Zn finger	893..914	CDD:275368
		C2H2 Zn finger	937..957	CDD:275368
		C2H2 Zn finger	966..986	CDD:275368
		C2H2 Zn finger	1205..1225	CDD:275368
		C2H2 Zn finger	1236..1257	CDD:275368
		C2H2 Zn finger	1266..1282	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24408
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100