DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cdc5 and MYB101

DIOPT Version :9

Sequence 1:	NP_001163313.1	Gene:	Cdc5 / 38062	FlyBaseID:	FBgn0265574	Length:	814	Species:	Drosophila melanogaster
Sequence 2:	NP_180805.1	Gene:	MYB101 / 817807	AraportID:	AT2G32460	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	529	Identity:	103/529 - (19%)
Similarity:	177/529 - (33%)	Gaps:	166/529 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IKGGVWRNTEDEILKAAVMKYGKNQWSRI---ASLLHRKSAKQCKARWYEWLDPSIKKTEWSREE 67
            :|.|.|..|||.||...|.|:|:..|:.:   :.||  :..|.|:.||...|.|::||..::.:|
plant    18 LKKGPWTTTEDAILTEYVRKHGEGNWNAVQKNSGLL--RCGKSCRLRWANHLRPNLKKGSFTPDE 80

  Fly    68 DEKLLHLAKLMPTQW-RTIAPIIGRTAAQCLERYEYLLDQAQR----------KEDGEDTMDD-- 119
            ::.::.|...:..:| |..:.:.|||..:....:...:.:.||          :..|.|..|:
plant    81 EKIIIDLHAKLGNKWARMASQLPGRTDNEIKNYWNTRMKRRQRAGLPLYPHEIQHQGIDIDDEFE 145

  Fly   120 ----PRKLKPGEIDPNPE-------------------------TKPARPDP-------------K 142
                ..:.:..::|.|.:                         :|..||||             .
plant   146 FDLTSFQFQNQDLDHNHQNMIQYTNSSNTSSSSSSFSSSSSQPSKRLRPDPLVSTNPGLNPIPDS 210

  Fly   143 DMDEDELEMLSEARARLANTQGK-----------------------------KAKRKAREKQLEE 178
            .||   .:|.|.....|.|...:                             ...|...:|.::.
plant   211 SMD---FQMFSLYNNSLENDNNQFGFSVPLSSSSSSNEVCNPNHILEYISENSDTRNTNKKDIDA 272

  Fly   179 ARRLATLQKRRELRAAGIGSGNRKRIKGIDYNA-EIPFEKRPAHGFYDT----SEEHLQKNEPDF 238
            ....:.|....|:|::...       .|:|.:. |:|..:||.|.|..:    :..||:  .|..
plant   273 MSYSSLLMGDLEIRSSSFP-------LGLDNSVLELPSNQRPTHSFSSSPIIDNGVHLE--PPSG 328

  Fly   239 NKMRQQDLDGELRSEKEERERKRDKQKLKQR---KENEVPTAMLQNMEPERKRSKLVLPTPQISD 300
            |       .|.|.:..||      .|.|.:.   |:..|.::.|  .|.:.||.|:......|..
plant   329 N-------SGLLDALLEE------SQALSRGGLFKDVRVSSSDL--CEVQDKRVKMDFENLLIDH 378

  Fly   301 MELQQVVKLGRASEMAKEIAGESGIETT----DALLADYSITPQVAATPRTPAPYTDRIMQEAQN 361
            :.......||....:..:....:.::.|    |.||.  |:.....:| .||.|...|: .|.||
plant   379 LNSSNHSSLGANPNIHNKYNEPTMVKVTVDDDDELLT--SLLNNFPST-TTPLPDWYRV-TEMQN 439

  Fly   362 MMALTHTETPLKGGLNTPLHESDFSGVLPKAASIATPNTVIATPFRTQREGGAATPGGFQTPSSG 426
                                         :|:.:|.|:.::..  ..|..|....|   ..|.|.
plant   440 -----------------------------EASYLAPPSGILMG--NHQGNGRVEPP---TVPPSS 470

  Fly   427 ALVPVKGAG 435
            ::.|:...|
plant   471 SVDPMASLG 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc5	NP_001163313.1	SANT	8..56	CDD:197842	18/50 (36%)
		Myb_DNA-bind_6	11..71	CDD:290632	21/62 (34%)
		SANT_CDC5_II	56..108	CDD:212557	10/52 (19%)
		SANT	60..104	CDD:197842	8/44 (18%)
		Myb_Cef	397..648	CDD:288664	8/39 (21%)
MYB101	NP_180805.1	SANT	17..>121	CDD:333364	29/104 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900