Protein Alignment Cdc5 and MYBL1

DIOPT Version :9

• Sequence 1: NP_001163313.1
• Gene: Cdc5 / 38062
• FlyBaseID: FBgn0265574
• Length: 814
• Species: Drosophila melanogaster
• Sequence 2: XP_016868944.1
• Gene: MYBL1 / 4603
• HGNCID: 7547
• Length: 770
• Species: Homo sapiens
• Alignment Length: 859
• Identity: 179/859 - (20%)
• Similarity: 295/859 - (34%)
• Gaps: 275/859 - (32%)

  Fly    11 WRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEDEKLLHLA 75
            |...||:.||..|.::|.:.|:.|||.|..:|..||:.||.:.|:|.:.|..|::|||::::.|.
Human    51 WTRDEDDKLKKLVEQHGTDDWTLIASHLQNRSDFQCQHRWQKVLNPELIKGPWTKEEDQRVIELV 115

  Fly    76 -KLMPTQWRTIAP-IIGRTAAQCLERYEYLLDQAQRKEDGEDTMDDPRKLKPGEIDPNPETKPAR 138
             |..|.:|..||. :.||...||.||:...|                          |||.|.:
Human   116 QKYGPKRWSLIAKHLKGRIGKQCRERWHNHL--------------------------NPEVKKS- 153

  Fly   139 PDPKDMDEDELEMLSEARARLANTQGKKAK-------------------RKAREK-----QLEEA 179
                ...|:|..::.||..||.|...:.||                   ||..::     .::..
Human   154 ----SWTEEEDRIIYEAHKRLGNRWAEIAKLLPGRTDNSIKNHWNSTMRRKVEQEGYLQDGIKSE 214

  Fly   180 RRLATLQKRRELRAAGIGSGNRKRIKGIDYNAEIPFEKRPAHGF-YDTSE----EHLQKNEPDFN 239
            |..:.||.:.......:.:.|:..|.     .:||       |: |.:.|    ||:|   |...
Human   215 RSSSKLQHKPCAAMDHMQTQNQFYIP-----VQIP-------GYQYVSPEGNCIEHVQ---PTSA 264

  Fly   240 KMRQQDLDGELRSEKEERERK-RDKQKLKQRKENEV-----PT----------AMLQNMEPERKR 288
            .::|..:|     |..::|:| ::.:.|....||||     |:          :.|.:.......
Human   265 FIQQPFID-----EDPDKEKKIKELEMLLMSAENEVRRKRIPSQPGSFSSWSGSFLMDDNMSNTL 324

  Fly   289 SKLVLPTPQISDMELQQVVKLGRASEMAKEIAGESGIETTDALLADYSITPQVAAT--------- 344
            :.|...|.:...|:..|.|. .:.:...|.:|.|:     :|:|:.....|:.|.|
Human   325 NSLDEHTSEFYSMDENQPVS-AQQNSPTKFLAVEA-----NAVLSSLQTIPEFAETLELIESFNL 383

  Fly   345 PRTPAPYTD------------RIMQEAQNMMALTHTETPLKGGLNTPL----HESDFSGVLPKAA 393
            .:.|..::|            .|......:|.:.|.|..::...|..|    .::..:|...:|.
Human   384 LQDPVAWSDVTSFDISDAAASPIKSTPVKLMRIQHNEGAMECQFNVSLVLEGKKNTCNGGNSEAV 448

  Fly   394 SIATPNTVIATPFRTQREGGAATPGGFQTPSSGALVPVKGAGGATGVVNTPAYVRDKLSINPEES 458
            .:.:||  ||.               |.||                    ||.:|.|      ..
Human   449 PLTSPN--IAK---------------FSTP--------------------PAILRKK------RK 470

  Fly   459 MGVTETPAHYKNYQKQLKSTLRDG--------------LSTLPAPRNDYEIVVP--EQEESERIE 507
            |.|..:|.          |.||||              |.|||...:.:....|  ||...|...
Human   471 MRVGHSPG----------SELRDGSLNDGGNMALKHTPLKTLPFSPSQFFNTCPGNEQLNIENPS 525

  Fly   508 TNSEPAVEDQADVDARLLAEQEAR-RKRELEKRSQVIQRSL----PRPTEVNTKILRPQSEKQNL 567
            ..|.|....:|.:...|..|...: :|..:..|:..|:||:    ||........|..|.:|...
Human   526 FTSTPICGQKALITTPLHKETTPKDQKENVGFRTPTIRRSILGTTPRTPTPFKNALAAQEKKYGP 590

  Fly   568 TE---------QQQAEELIKHEMITMQLYDSVKDPVPGQSQHKLEQLQSYFKANPYEDISQQELA 623
            .:         ::...|::|.|..|........:|.                   |:...|:..|
Human   591 LKIVSQPLAFLEEDIREVLKEETGTDLFLKEEDEPA-------------------YKSCKQENTA 636

  Fly   624 KAKQMLTEEMEVVKERMAHGELPLDVYAQVWQECLGQVLY-----LPSQHRYT------------ 671
            ..|::             ...|.||.:.:  :|...|:|.     :.|::|:|
Human   637 SGKKV-------------RKSLVLDNWEK--EESGTQLLTEDISDMQSENRFTTSLLMIPLLEIH 686

  Fly   672 --RANLASKKDRLESAEKRLETNRRHMAKEAKRCGKIEKKLKILTGGYQARAQ---VLIKQLQDT 731
              |.||..:|..:.|..|.....::.......:..|:||.|       |:..:   |:..:.:|.
Human   687 DNRCNLIPEKQDINSTNKTYTLTKKKPNPNTSKVVKLEKNL-------QSNCEWETVVYGKTEDQ 744

  Fly   732 YGQIEQNSVSLSTF 745
            ....||....|||:
Human   745 LIMTEQARRYLSTY 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc5	NP_001163313.1	SANT	8..56	CDD:197842	18/44 (41%)
		Myb_DNA-bind_6	11..71	CDD:290632	24/59 (41%)
		SANT_CDC5_II	56..108	CDD:212557	19/53 (36%)
		SANT	60..104	CDD:197842	17/45 (38%)
		Myb_Cef	397..648	CDD:288664	52/280 (19%)
MYBL1	XP_016868944.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5147
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810