Protein Alignment Ptpmeg and Gopc

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_001186201.1
• Gene: Gopc / 94221
• MGIID: 2149946
• Length: 463
• Species: Mus musculus
• Alignment Length: 569
• Identity: 112/569 - (19%)
• Similarity: 183/569 - (32%)
• Gaps: 223/569 - (39%)

  Fly    83 PGDV--VRWVDA-QKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNI 144
            ||.|  .||::. :|:|.|....|.|....:            ||.  |.:.| |:
Mouse    26 PGGVSMFRWLEVLEKEFDKAFVDVDLLLGEI------------DPD--QADIT-YE--------- 66

  Fly   145 LLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLH---- 205
              |:...:|.:.|             |..|.|:...:|.:.                |||.
Mouse    67 --GRQKMTSLSSC-------------FAQLCHKAQTVSQIN----------------HKLEAQLV 100

  Fly   206 --RGQL-PADAEYNYLE---HAKRLELYG--IDLHRAT----DSNGKELQLGVSAVGLLVFQHSL 258
              |.:| ...||...||   |.:.|:|:.  :.||..|    ||...:.:|.|.:|..|  :..|
Mouse   101 DLRSELTETQAEKVVLEKEVHEQLLQLHSTQLQLHAKTGQSVDSGAIKAKLSVHSVEDL--EREL 163

  Fly   259 RVNTFSWSKMVKVSFKRKDFFIQLRREPSENYDTLLGFGMSSHKHAKALWKSCVEHHSFFRLKRP 323
            ..|     |..||...|.:..::|.|:.:|          :..:|...|
Mouse   164 EAN-----KTEKVKEARLEAEVKLLRKENE----------ALRRHIAVL---------------- 197

  Fly   324 HRLSRFLNISLGSKFYYSGRTELQAVQESKQRGRIHKVFVRSPSKRLLGAAGGVGTSGSSGGTPM 388
              .:......|.:|:.           :.:..||:.::       :|||
Mouse   198 --QAEVYGARLAAKYL-----------DKELAGRVQQI-------QLLG---------------- 226

  Fly   389 QQHSGSESANSHNNGKPAGAGTILTITKTSRPHDNKVTSKEADSMPRKAWEQQSDEYDIQLDVGF 453
            :...|           ||              ||             |.|.|...|..:......
Mouse   227 RDMKG-----------PA--------------HD-------------KLWNQLEAEIHLHRHKTV 253

  Fly   454 IEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQP--ESGSDLITIR----LQADEQ 512
            |..|..|.:...|...||                    ||.|.  :....:..||    |:.|.:
Mouse   254 IRACRGRNDLKRPMQAPP--------------------GHDQDSLKKSQGVGPIRKVLLLKEDHE 298

  Fly   513 GRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCR 577
            | .|.::.||.:..:|:.:|::.|..||||| ..:..||.:|.:||.::...:|::.|.::...|
Mouse   299 G-LGISITGGKEHGVPILISEIHPGQPADRC-GGLHVGDAILAVNGVNLRDTKHKEAVTILSQQR 361

  Fly   578 HQASGELLLTVRPQRSAPLLLEEEPLYQYVPES--------DEIGSHSN 618
            .:...|::..      ||.:..::...:|..||        ||:....|
Mouse   362 GEIEFEVVYV------APEVDSDDENVEYEDESGHRYRLYLDELEGSGN 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604	34/163 (21%)
		FERM_N	38..102	CDD:286467	8/21 (38%)
		FERM_M	125..232	CDD:278785	22/118 (19%)
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010	21/99 (21%)
		FA	333..369	CDD:285894	4/35 (11%)
		PDZ_signaling	502..589	CDD:238492	25/90 (28%)
		Y_phosphatase	666..955	CDD:278528
		PTPc	668..955	CDD:238006
Gopc	NP_001186201.1	PDZ_signaling	287..369	CDD:238492	25/83 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910