| Sequence 1: | NP_001163309.2 | Gene: | Ptpmeg / 38059 | FlyBaseID: | FBgn0261985 | Length: | 974 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006713873.1 | Gene: | KALRN / 8997 | HGNCID: | 4814 | Length: | 2988 | Species: | Homo sapiens |
| Alignment Length: | 1166 | Identity: | 215/1166 - (18%) |
|---|---|---|---|
| Similarity: | 352/1166 - (30%) | Gaps: | 450/1166 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 26 DKKTPQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLFPQKPGDVVRWV 90
Fly 91 DAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIK---RNILLGKLPCS 152
Fly 153 SNTQCLLASYTVQSELGDF--------------------------------NALEHQPG--YLSG 183
Fly 184 M--------------------------QLLCDQTTEAERKVGE-----LHKLHRGQLPADAE--- 214
Fly 215 --YNY--------------LEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVNTF 263
Fly 264 SWSKMVKVSF------------------KRKDFFIQLRREPSENYDTLL----GFGMSSHKHAKA 306
Fly 307 LWKSC----VEHHSFFRLKRPHRLSRFLNISLGSKFYYSGRTELQAVQESKQRGRIHKVFVRS-- 365
Fly 366 -----------PSKRLLGAAGGVGTSGS-----------SGGTPMQQHSGSESANSHNNGKPAGA 408
Fly 409 GTILTITKTSRPHDNKVTSKE--------ADSMPRKAWEQQSDEYDIQLDVGFIEQCTRRFESAS 465
Fly 466 PSPMPPAYSSGQHSPILLPTTIADA----VGHQQPESGSDLITI---RLQADEQGRYGFN----- 518
Fly 519 -VKGGVDLS---LPVQVSKVVPHTPADRCTPRVCEGD------------------EVLMINGRDV 561
Fly 562 H-------GLRH-----EQVVAMIRDCRHQASGELLLTVRPQRSAPL-----LLEEEPLYQYVPE 609
Fly 610 S--------------------DEIGSHSNLLDGDAL----------FTQSLLLLSDGL----ASG 640
Fly 641 A----------LLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPY-------------DCTR 682
Fly 683 VSLVNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESG 747
Fly 748 RQKCHQY------------WPVTGEELQLAEGFSVRCLSEKPDETGSFV--FREFVLKDKH---- 794
Fly 795 ------------EQRHIHHMQYLAWPDHCVPSDPNLFLEFTER-------------VRAARNRTL 834
Fly 835 -LQEIEESL--KQVRLMDADADADENGGLMRERKCAASN----GATPEDETPVSTSVHQCI 888 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Ptpmeg | NP_001163309.2 | B41 | 35..232 | CDD:214604 | 50/283 (18%) |
| FERM_N | 38..102 | CDD:286467 | 15/63 (24%) | ||
| FERM_M | 125..232 | CDD:278785 | 32/193 (17%) | ||
| FERM_C_PTPN4_PTPN3_like | 226..320 | CDD:270010 | 22/119 (18%) | ||
| FA | 333..369 | CDD:285894 | 7/48 (15%) | ||
| PDZ_signaling | 502..589 | CDD:238492 | 27/128 (21%) | ||
| Y_phosphatase | 666..955 | CDD:278528 | 55/286 (19%) | ||
| PTPc | 668..955 | CDD:238006 | 55/284 (19%) | ||
| KALRN | XP_006713873.1 | SEC14 | 41..179 | CDD:214706 | |
| SPEC | 192..412 | CDD:238103 | 29/173 (17%) | ||
| SPEC | 313..538 | CDD:238103 | 46/263 (17%) | ||
| SPEC | 539..768 | CDD:238103 | 44/260 (17%) | ||
| SPEC | 893..1131 | CDD:238103 | 48/254 (19%) | ||
| SPEC | <1101..1240 | CDD:295325 | 24/147 (16%) | ||
| RhoGEF | 1286..1456 | CDD:238091 | 3/21 (14%) | ||
| PH1_Kalirin_Trio_like | 1463..1585 | CDD:270060 | |||
| PH | 1496..1581 | CDD:278594 | |||
| SH3_Kalirin_1 | 1651..1710 | CDD:212786 | |||
| SH3-RhoG_link | 1708..1934 | CDD:293215 | |||
| RhoGEF | 1935..2105 | CDD:279015 | |||
| PH2_Kalirin_Trio_p63RhoGEF | 2109..2243 | CDD:270061 | |||
| PH | 2142..2228 | CDD:278594 | |||
| SH3_Kalirin_2 | 2327..2385 | CDD:212787 | |||
| I-set | 2473..2567 | CDD:254352 | |||
| Ig | 2490..2564 | CDD:143165 | |||
| FN3 | 2571..2662 | CDD:238020 | |||
| S_TKc | 2686..2940 | CDD:214567 | |||
| STKc_Kalirin_C | 2692..2939 | CDD:271017 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||