DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg and snta1

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_001072684.1	Gene:	snta1 / 780141	XenbaseID:	XB-GENE-962569	Length:	473	Species:	Xenopus tropicalis

Alignment Length:	152	Identity:	37/152 - (24%)
Similarity:	64/152 - (42%)	Gaps:	30/152 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   465 SPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESG--SDLI----TIRLQADEQGRYGFNVKGGV 523
            :|.|.|.|...             .|:...:|..|  ..||    |:|:...:.|..|.::|||.
Frog    37 TPEPEPGAAEE-------------KALNGAEPAGGVPESLINLRRTVRVLKQDAGGLGVSIKGGR 88

  Fly   524 DLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTV 588
            :..:|:.:||:.....|| .|..:..||.:|.:||.|:....|:..|..::    :...|::|.|
Frog    89 ENKMPILISKIFKGLAAD-LTGSLYVGDAILSVNGVDLSEATHDDAVQALK----KTGKEVVLEV 148

  Fly   589 RPQRSAPLLLEEEPLYQYVPES 610
            :      .:.|..|.::..|.|
Frog   149 K------YMKEISPYFKGSPPS 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	25/90 (28%)
		Y_phosphatase	666..955	CDD:278528
		PTPc	668..955	CDD:238006
snta1	NP_001072684.1	PDZ_signaling	68..149	CDD:238492	23/85 (27%)
		PHsplit_syntrophin	<188..245	CDD:269960
		PH	262..369	CDD:306640
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910