Protein Alignment Ptpmeg and ptpru

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_012812827.1
• Gene: ptpru / 733850
• XenbaseID: XB-GENE-922688
• Length: 1439
• Species: Xenopus tropicalis
• Alignment Length: 580
• Identity: 141/580 - (24%)
• Similarity: 209/580 - (36%)
• Gaps: 187/580 - (32%)

  Fly   472 AYSSGQHSPILLPTTIADAVGHQQPESG----------SDLITIRLQADEQGRYGFNVKGGVDLS 526
            :|...:..|..||......||..:...|          ..||.::..:..:|....|.
 Frog   654 SYVGAEIPPTDLPRDTPFIVGDNRSYGGYWNPPLDPRRGYLIYLQAASHHRGETRLNC------- 711

  Fly   527 LPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGL-----RHEQVVAMIRDCRHQASGE--- 583
              |::::..|...:.|.:......||:.::.|....||     ....|:.::|..|.|.|..
 Frog   712 --VRIARKAPCKDSQRSSMAPQRSDEMGLVLGICAGGLVVFIILLGAVILIVRKGRTQFSYAYYP 774

  Fly   584 ----LLLTVRPQR----------------SAPLLLEEEP----LYQY-----VPESDEIGSHSNL 619
                |..:..|.|                ..|.||:||.    |:.|     .|....:...|:|
 Frog   775 KPIGLTKSALPSRHENSNCAAPREHTKMTDQPTLLQEEAALAFLHSYNTRVGEPRVGSVTESSSL 839

  Fly   620 LDG-------------------------DALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAIT 659
            |.|                         |.|...:.:.:::|.   ....:||..:.       .
 Frog   840 LGGSPRRGGGRKGSPYHTGQLHPAVRVADLLQHINQMKVAEGY---GFKQEYESFFD-------W 894

  Fly   660 EARKPANAPKNRYRDISP-YDCTRV---SLVNSLTGDYINANYVNMEIPGGAV---NRYIATQGP 717
            :..|..:..|.| :||.| |:..||   .|....:.:.|||||:::.|.....   |.:||||||
 Frog   895 DVSKKKDKGKGR-QDIPPNYERHRVRLHPLQAECSSEEINANYIDIRINREGYHRSNHFIATQGP 958

  Fly   718 LASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWPVTGEEL-----------QLAEGFSVR 771
            ......||||||.||....:||:|.::|.||.||.:|||.|.:..           .||| :|||
 Frog   959 KQDMIYDFWRMVWQEHVSSIVMITKLVEVGRVKCSKYWPDTSDTYGDIRVTLLNTETLAE-YSVR 1022

  Fly   772 CLSEKPDETGSFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQ 836
            .|:  .:..|..|        :||.:..|   :|:||||.||......|.|..||::
 Frog  1023 TLT--LERRGYTV--------RHEVKQFH---FLSWPDHGVPYHATGLLAFIRRVKS-------- 1066

  Fly   837 EIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSA 901
                                               :||.|.               .||:|||||
 Frog  1067 -----------------------------------STPPDA---------------GPVVVHCSA 1081

  Fly   902 GIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCE-----CIC 956
            |.||||..|::|..|.:.|....|...:.|:|:..:|..|||...||.|:.:     |:|
 Frog  1082 GAGRTGCYIVLDVMLDMAECEGVVDIYNCVKTLCSRRINMVQTQEQYVFIHDAILEACLC 1141

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	18/98 (18%)
		Y_phosphatase	666..955	CDD:278528	94/311 (30%)
		PTPc	668..955	CDD:238006	94/309 (30%)
ptpru	XP_012812827.1	MAM	27..183	CDD:366209
		IG_like	192..278	CDD:214653
		fn3	287..366	CDD:365830
		fn3	490..568	CDD:365830
		PTP_DSP_cys	931..1141	CDD:391942	86/281 (31%)
		PTP_DSP_cys	1227..1431	CDD:391942

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910