DRSC - DRSC Integrative Ortholog Prediction Tool

Protein Alignment Ptpmeg and PTPRS

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_002841.3	Gene:	PTPRS / 5802	HGNCID:	9681	Length:	1948	Species:	Homo sapiens

Alignment Length:		Identity:	/ - (0%)
Similarity:	/ - (0%)	Gaps:	/ - (0%)

- Green bases have known domain annotations that are detailed below.

Gene	Sequence	Domain	Region	External ID
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492
		Y_phosphatase	666..955	CDD:278528
		PTPc	668..955	CDD:238006
PTPRS	NP_002841.3	Ig	32..120	CDD:299845
		I-set	33..124	CDD:254352
		Important for binding to glycosaminoglycan chains. /evidence=ECO:0000250\|UniProtKB:B0V2N1	68..72
		IG_like	141..234	CDD:214653
		Ig2_RPTP_IIa_LAR_like	152..235	CDD:143215
		IG_like	251..328	CDD:214653
		Ig3_RPTP_IIa_LAR_like	259..327	CDD:143216
		FN3	332..421	CDD:238020
		FN3	428..520	CDD:238020
		FN3	525..613	CDD:238020
		FN3	621..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	700..724
		FN3	723..828	CDD:238020
		FN3	838..920	CDD:238020
		FN3	932..1029	CDD:238020
		FN3	1037..>1097	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1311..1340
		PTPc	1392..1647	CDD:214550
		PTPc	1418..1647	CDD:238006
		Substrate binding. /evidence=ECO:0000250	1589..1595
		PTPc	1679..1938	CDD:214550
		PTPc	1708..1938	CDD:238006
Blue background indicates that the domain is not in the aligned region.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910