Protein Alignment Ptpmeg and SNTG2

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_016859850.1
• Gene: SNTG2 / 54221
• HGNCID: 13741
• Length: 540
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 97/420 - (23%)
• Similarity: 149/420 - (35%)
• Gaps: 159/420 - (37%)

  Fly   430 ADS---MPRKAW----------------EQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSS 475
            |||   ..|:.|                |:..:.|||:|      :.|:.
Human     8 ADSAACFTRRTWHQLFEQTKTTIALLYDEESENAYDIRL------KLTKE--------------- 51

  Fly   476 GQHSPILLPTTIADAV----GHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVP 536
                  :|.....|.|    .||    |.:..|:.|:....|..|.::|||.:.::||.:||:..
Human    52 ------VLTIQKQDVVCVGGSHQ----GRNRRTVTLRRQPVGGLGLSIKGGSEHNVPVVISKIFE 106

  Fly   537 HTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEE 601
            ...||: |..:..||.||.:||..|....||:||.::|:    |..|:.:||...|.||..| :.
Human   107 DQAADQ-TGMLFVGDAVLQVNGIHVENATHEEVVHLLRN----AGDEVTITVEYLREAPAFL-KL 165

  Fly   602 PLYQYVPESD-EIGSHSNLLDG-------------------------------DALF-------- 626
            ||....|.|| ..|:.|.|.|.                               |.|.
Human   166 PLGSPGPSSDHSSGASSPLFDSGLHLNGNSSTTAPSSPSSPIAKDPRYEKRWLDTLSVPLSMARI 230

  Fly   627 ------TQSL------LLLSDGLASGAL---LAQYELMYRKNPDLAITEA----RKPANAPKNRY 672
                  |:.|      :|..||::||.|   .||....:.:.....|.|.    .|.||
Human   231 SRYKAGTEKLRWNAFEVLALDGVSSGILRFYTAQDGTDWLRAVSANIRELTLQNMKMAN------ 289

  Fly   673 RDISPYDCTRVSLVNSLTGDYINANYVNMEIPGGAVN-----RYIATQGP---LAST----TTDF 725
            :..||.|            ..::..:||.::.|...:     :::|.:||   :.||    |.|:
Human   290 KCCSPSD------------QVVHMGWVNEKLQGADSSQTFRPKFLALKGPSFYVFSTPPVSTFDW 342

  Fly   726 WRMVQQESSHLLVMLTTVMESGRQKCHQYW 755
            .|  .:.:.||..:|.        |.|::|
Human   343 VR--AERTYHLCEVLF--------KVHKFW 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	29/86 (34%)
		Y_phosphatase	666..955	CDD:278528	21/102 (21%)
		PTPc	668..955	CDD:238006	20/100 (20%)
SNTG2	XP_016859850.1	PDZ_signaling	73..154	CDD:238492	29/85 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910