DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg and Ptp61F

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_476687.1	Gene:	Ptp61F / 38160	FlyBaseID:	FBgn0267487	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	329	Identity:	96/329 - (29%)
Similarity:	137/329 - (41%)	Gaps:	92/329 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   652 KNPDLAITEARKPANAPKNRYRDISPYDCTRVSLVNSLTGDYINANYVNMEIPGGAVNRYIATQG 716
            |....:.:|:.:..|...|||||::|||.:|:.|... :.||||||.|.:|   .|..:||.|||
  Fly    46 KEKQFSTSESERHTNRGLNRYRDVNPYDHSRIVLKRG-SVDYINANLVQLE---RAERQYILTQG 106

  Fly   717 PLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWP---------------VTGEELQLAE 766
            ||..|...||.||.::.|..::||..:||..:.|||.|||               :|.|.::|
  Fly   107 PLVDTVGHFWLMVWEQKSRAVLMLNKLMEKKQIKCHLYWPNEMGADKALKLPHVKLTVELVRL-- 169

  Fly   767 GFSVRCLSEKPDET-GSFVFREFVLKDKHEQ--RHIHHMQYLAWPDHCVPSDPNLFLEFTERVRA 828
                        || .:||.|.|.|.|...|  |.:....|..|||..:||.||.||:|.::||
  Fly   170 ------------ETYQNFVRRWFKLTDLETQQSREVMQFHYTTWPDFGIPSSPNAFLKFLQQVR- 221

  Fly   829 ARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANP 893
                                       ::|                            |:|....
  Fly   222 ---------------------------DSG----------------------------CLSRDVG 231

  Fly   894 PVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVSQYRFVCECICAA 958
            |.:|||||||||:|...|:|..|.|::.........::..:|..|..::|...|..|..:.|...
  Fly   232 PAVVHCSAGIGRSGTFCLVDCCLVLIDKYGECNVSKVLCELRSYRMGLIQTADQLDFSYQAIIEG 296

  Fly   959 YMKI 962
            ..|:
  Fly   297 IKKL 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492
		Y_phosphatase	666..955	CDD:278528	92/306 (30%)
		PTPc	668..955	CDD:238006	91/304 (30%)
Ptp61F	NP_476687.1	PTPc	34..295	CDD:214550	95/322 (30%)
Ptp61F	NP_476687.1	PTPc	62..295	CDD:238006	92/306 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443548
Domainoid	1	1.000	133	1.000	Domainoid score	I1104
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.930