Protein Alignment Ptpmeg and PTPRQ

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_016874762.1
• Gene: PTPRQ / 374462
• HGNCID: 9679
• Length: 2536
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 151/601 - (25%)
• Similarity: 221/601 - (36%)
• Gaps: 202/601 - (33%)

  Fly   480 PILLPTTIADAVGHQQPESGSDLITIRL----QADEQG----------RYGFNVKGGVDLSLPVQ 530
            |...||.|.||.|.....|.:  ||||:    .:|:.|          ..|....|.|.......
Human  1970 PKTKPTPIYDATGKLLVTSTT--ITIRMPICYYSDDHGPIKNVQVLVTETGAQHDGNVTKWYDAY 2032

  Fly   531 VSKVVPH-----TPADRCTPRVCE--GDEVLMINGRD-----------------------VHGLR 565
            .:|..|:     .|...||....:  |:|.:.|.|.|                       :...|
Human  2033 FNKARPYFTNEGFPNPPCTEGKTKFSGNEEIYIIGADNACMIPGNEDKICNGPLKPKKQYLFKFR 2097

  Fly   566 HEQVVAMIRDCRH------------QASGELLLTVRPQRSAPLLL------------EEEPLYQY 606
            ...::....|..:            :.:.|::|:|.....:.:||            :::....|
Human  2098 ATNIMGQFTDSDYSDPVKTLGEGLSERTVEIILSVTLCILSIILLGTAIFAFARIRQKQKEGGTY 2162

  Fly   607 VPESDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYE--------------LMYRKN---- 653
            .|:..||  ....|..|.|.|.:.|.|.|     ..|.:|.              |.|||:
Human  2163 SPQDAEI--IDTKLKLDQLITVADLELKD-----ERLTRYSSFFFRRKEIFVIQLLSYRKSIKPI 2220

  Fly   654 -------------------------------PDLAITEARKPANAPKNRYRDISPYDCTRVSLV- 686
                                           .||:.|:|..|.|..|||:.:|.||:..||.|:
Human  2221 SKKSFLQHVEELCTNNNLKFQEEFSELPKFLQDLSSTDADLPWNRAKNRFPNIKPYNNNRVKLIA 2285

  Fly   687 -NSLTG-DYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQ 749
             .|:.| |||||:|::..:   ..|.:|||||||..|..||||||.:..:..|||||...|.||.
Human  2286 DASVPGSDYINASYISGYL---CPNEFIATQGPLPGTVGDFWRMVWETRAKTLVMLTQCFEKGRI 2347

  Fly   750 KCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFVFREFVLKDKHEQRH-----IHHMQYLAWPD 809
            :||||||...:.:.:.....:..|.|.       |..::.::|...:||     :....:.|||:
Human  2348 RCHQYWPEDNKPVTVFGDIVITKLMED-------VQIDWTIRDLKIERHGDCMTVRQCNFTAWPE 2405

  Fly   810 HCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATP 874
            |.||.:....:.|.:.|||:|                                           .
Human  2406 HGVPENSAPLIHFVKLVRASR-------------------------------------------A 2427

  Fly   875 EDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRA 939
            .|.|               |:|||||||:|||||.|.:|.....:...:.|....:|..:|.:|.
Human  2428 HDTT---------------PMIVHCSAGVGRTGVFIALDHLTQHINDHDFVDIYGLVAELRSERM 2477

  Fly   940 CMVQNVSQYRFVCECI 955
            |||||::||.|:.:||
Human  2478 CMVQNLAQYIFLHQCI 2493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	23/142 (16%)
		Y_phosphatase	666..955	CDD:278528	93/296 (31%)
		PTPc	668..955	CDD:238006	92/294 (31%)
PTPRQ	XP_016874762.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910