Protein Alignment Ptpmeg and Ptp52F

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_611093.2
• Gene: Ptp52F / 36790
• FlyBaseID: FBgn0034085
• Length: 1433
• Species: Drosophila melanogaster
• Alignment Length: 1048
• Identity: 219/1048 - (20%)
• Similarity: 351/1048 - (33%)
• Gaps: 368/1048 - (35%)

  Fly    89 WVDAQKQFKKQCSSVSLDNDAVPLLEFRVKFFVSDPSRLQEEFTRYQFYLQIKRNILLGKL-PCS 152
            |::..|..:.:..|::..|..|          |.|.:.|..:....|.....|.| |.|:| ...
  Fly   484 WMEDDKLVEVEALSITTQNTTV----------VFDKNLLACQVYIIQIIPYTKEN-LDGQLRQVG 537

  Fly   153 SNTQCLLASYT--------VQSELGD---FNALEHQPGYLSGMQLL-----CDQTTE-----AER 196
            ..|:..:..||        ..||..|   |||     .|.:....:     |:.||:     |||
  Fly   538 VETKAAIVDYTKVKLEMKNAGSEFIDLIAFNA-----DYNNSCPTIFALFTCNATTQVRNPYAER 597

  Fly   197 KVGELHKLHRGQLPADAEYNYLEHAKRLELYGI----------DLHRAT--DSNGKELQLGVSAV 249
            .| |.|..............|..:..::.||.:          |:|..|  ....:.:.|..|.|
  Fly   598 YV-EGHSKQGFNASLSPLSPYATYVCKVILYNVAGPSEPVVDADMHTTTYFPEQPESVMLEKSTV 661

  Fly   250 GLLVFQHSLRVNTFSWSKMVKVSFKRKD--FFI-------------QLRREPSENYDTLL----- 294
            ..|:|.......|....|..:....|.:  :|:             :.:.:||.|:..|.
  Fly   662 SSLLFNWQPPTYTNGPIKYYQAFLMRHEASYFVPADCAIVEQDTKSETKGDPSVNFTGLAPAVRY 726

  Fly   295 --------GFGMSSH----------------------------------KHAKALWK-SCVEHH- 315
                    .|||..:                                  .:....|| .|..:.
  Fly   727 MMQVAAQNDFGMGVYTEPVIGITLPAVSDSVTQLTVLTQGPVNNNAVYEANVTITWKVPCKSNGD 791

  Fly   316 -SFFRLK--------RPHRLSRFLNISLGSKFYYSGR-----TELQ-----AVQES--------- 352
             .:|:|.        .|....|.:.:..|:|   .||     ||:|     .|:.|
  Fly   792 IEYFQLAFNGTRNNFAPVSFERRVELDTGNK---QGRMSYTETEMQPQFDYTVEVSVKNRDVEQL 853

  Fly   353 ------------------------KQRGRIHK-------VFVRSPSKRLLGAAGGVG------TS 380
                                    :.|..:.:       ..||.|:..:..|:|.:.      :.
  Fly   854 SSSVPGSWQSPAGLPTIPSDELIKQMRANVEETSNPTKTAIVRLPADIMTSASGDIKWMALMISQ 918

  Fly   381 GSSGGTPMQQHSGSESANSHNNGKPAGA-GT----ILTITKTSRPHDNKVTSKEADSMPRKAWEQ 440
            .:..|.|..::..|.......:.:.||| ||    :...|...|.|...|..:..|.      |.
  Fly   919 KNCAGVPHLKYDVSSDWPKVLSYQEAGADGTGDCSLEYQTTEERWHPEPVQRQRRDG------EV 977

  Fly   441 QSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESG-SDLIT 504
            .||| :|...:| :::|         |.:...|.:|.    |||.|..:.|......|| ||...
  Fly   978 TSDE-EIVFTIG-LDKC---------SEVQKTYCNGP----LLPDTDYNVVVRLFTASGYSDAAV 1027

  Fly   505 IRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQV 569
            :          .|..|..:.::| :.||              ||....:..:.|..|..:|..
  Fly  1028 L----------NFKTKAAIKVTL-ILVS--------------VCSCLLLAFVLGLTVLWVRKR-- 1065

  Fly   570 VAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSHSNLLDGDALFTQSLLLLS 634
            :|..||     ||:.:              |:|....:.::..|           .:|:
  Fly  1066 LAWKRD-----SGQGI--------------EDPFGNVIAKNFAI-----------FYTE------ 1094

  Fly   635 DGLASGALLAQYELMYRKNPDLAITEARKPANAP-----KNRYRDISPYDCTRVSL-VNSLTGDY 693
                    :|:.|.:.|:..::.:.......:|.     ||||.||.|||..||.| :::...||
  Fly  1095 --------VAKPEKLAREFKEITVVALELSYSASELGCHKNRYADIFPYDKNRVILDIDAEGSDY 1151

  Fly   694 INANYVNMEIPGGAVNR--YIATQGPLASTTTDFWRMVQQESSHLLVMLTTVMESGRQKCHQYWP 756
            |||::::     |...:  |||||||...:..|||||:.|.:..::|.:|...|....|||:|:|
  Fly  1152 INASFID-----GHTRKKEYIATQGPKPESVMDFWRMILQYNVRVIVQVTQFREGNTIKCHEYYP 1211

  Fly   757 VTGEELQLAEGFSVRCLS----EKPDETG-SFVFREFVLKDKHEQRHIHHMQYLAWPDHCVPSDP 816
            ..      ..|.:|...|    |..|.|. :.|..::.||:|     :.|..:..||||.||.||
  Fly  1212 YN------VRGLTVTIKSKEVLELYDRTELTVVHDKYGLKEK-----VIHYYFKKWPDHGVPEDP 1265

  Fly   817 NLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATPEDETPVS 881
            ...:.|.::|:|                                  |::.:.|
  Fly  1266 MHLIMFVKKVKA----------------------------------EKRPSYS------------ 1284

  Fly   882 TSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRACMVQNVS 946
                        |::||||||:||||..|.:|..:..:::...:...:.|:.:|.||..|||...
  Fly  1285 ------------PIVVHCSAGVGRTGTFIGLDLIMQRLKSESKINIFETVKKLRFQRMKMVQTQQ 1337

  Fly   947 QYRFVCEC 954
            ||.|:..|
  Fly  1338 QYTFLYAC 1345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604	37/174 (21%)
		FERM_N	38..102	CDD:286467	2/12 (17%)
		FERM_M	125..232	CDD:278785	30/138 (22%)
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010	25/170 (15%)
		FA	333..369	CDD:285894	13/85 (15%)
		PDZ_signaling	502..589	CDD:238492	15/86 (17%)
		Y_phosphatase	666..955	CDD:278528	88/302 (29%)
		PTPc	668..955	CDD:238006	87/300 (29%)
Ptp52F	NP_611093.2	FN3	648..749	CDD:238020	16/100 (16%)
		PTPc	1100..1345	CDD:214550	88/318 (28%)
		PTPc	1125..1348	CDD:238006	87/295 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45443569
Domainoid	1	1.000	133	1.000	Domainoid score	I1104
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840