Protein Alignment Ptpmeg and Frmd5

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: XP_038962754.1
• Gene: Frmd5 / 311362
• RGDID: 1561554
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 151/547 - (27%)
• Similarity: 251/547 - (45%)
• Gaps: 91/547 - (16%)

  Fly    15 RLRGGGPELARDKKTPQRQQCVTVLFLDDITHTFRIEKRAKGSELLDQVFQYLELSERDYFGLLF 79
            ||..|      ..::.:|:...||..|||..:|..|::.|||..|.|.:..:|.|.|:||||:.|
  Rat     4 RLMSG------SSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRF 62

  Fly    80 PQKPGDVVRWVDAQKQFKKQCSSVSLDNDAVPL-LEFRVKFFVSDPSRLQEEFTRYQFYLQIKRN 143
            .. |.....|::..|...||..|      ..|. :.|||||:.:||:.|:||.|||..:|||||:
  Rat    63 VD-PDKQRHWLEFTKSVVKQLRS------QPPFTMCFRVKFYPADPAALKEEITRYLVFLQIKRD 120

  Fly   144 ILLGKLPCSSNTQCLLASYTVQSELGDFNALEHQPGYLSGMQLLCDQTTEAERKVGELHKLH-RG 207
            :..|:|.|.::...|||:|.:|:|:||::..:|..||.|..|.....:.:.|:|:.|:||.. .|
  Rat   121 LYHGRLLCKTSDAALLAAYILQAEIGDYDPGKHPEGYSSKFQFFPKHSEKLEKKIAEIHKTELSG 185

  Fly   208 QLPADAEYNYLEHAKRLELYGIDLHRATDSNGKELQLGVSAVGLLVFQHSLRVN----------- 261
            |.||.:|.|:|..|:.||.||:|.|...|.:|....|..:..|.:|.|.:.||:
  Rat   186 QTPATSELNFLRKAQTLETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKCILFASFT 250

  Fly   262 ------------------TFSWSKMVKVSFKRKDFFIQLRREPSENYDTLLGFGMSSHKHAKALW 308
                              ..||:::.|:.|:.|.|::.:.::  |....:|.:...:.:..|.||
  Rat   251 AAIHWAGGFKDFSTITPKPLSWNEVTKLKFEGKTFYLYVSQK--EEKKIILTYFAPTPEACKHLW 313

  Fly   309 KSCVEHHSFFRLKRPHRLSRFLNISL---GSKFYYSGRTELQAVQES----KQRGRIHKVFVRSP 366
            |..:|:.:|::|::..::....:.:|   ||:|.||||...:.::.|    ::...||:..: .|
  Rat   314 KCGIENQAFYKLEKSSQVRTVSSSNLFFKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGM-VP 377

  Fly   367 SKRLLGAAGG-------------VGTSGSSGGTPMQQHSGSESANSHNNGKPAGAGTILTITKTS 418
            |:.......|             |..|...|...::..:.|....|.::|     .|.|...::|
  Rat   378 SRSCPSITHGPRLSSVPRTRRRAVHISIMEGLESLRDSAHSTPVRSSSHG-----DTFLPHVRSS 437

  Fly   419 RPHDNK---VTSKEADSMPRKAWEQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSP 480
            |...|:   |.:.||.|...........|:.::|.:     .:|:...|:.|     ....:.|.
  Rat   438 RADSNERVAVIADEAYSPADSVLPTPVAEHSLELML-----LSRQINGATCS-----IEEEKESE 492

  Fly   481 ILLPT-TIADAVGHQ-----QPESGSD 501
            ...|| |.|:|:|.:     |...||:
  Rat   493 TSTPTSTEAEALGGELRALCQGHGGSE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604	79/198 (40%)
		FERM_N	38..102	CDD:286467	24/63 (38%)
		FERM_M	125..232	CDD:278785	45/107 (42%)
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010	26/122 (21%)
		FA	333..369	CDD:285894	13/42 (31%)
		PDZ_signaling	502..589	CDD:238492	151/547 (28%)
		Y_phosphatase	666..955	CDD:278528
		PTPc	668..955	CDD:238006
Frmd5	XP_038962754.1	B41	19..210	CDD:214604	79/197 (40%)
		PH-like	191..324	CDD:418428	32/134 (24%)
		FA	338..383	CDD:400882	13/45 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910