DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg and Sntg2

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	XP_006240029.1	Gene:	Sntg2 / 298936	RGDID:	1311276	Length:	540	Species:	Rattus norvegicus

Alignment Length:	288	Identity:	74/288 - (25%)
Similarity:	111/288 - (38%)	Gaps:	50/288 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 VGHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLM 555
            :|...|  |::..|:.|:....|..|.::|||.:..:||.:||:.....||: |..:..||.||.
  Rat    62 IGGAPP--GANHRTVTLRRQPVGGLGLSIKGGAEHGVPVVISKIFKDQAADQ-TEMLFIGDAVLQ 123

  Fly   556 INGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSHSNLL 620
            :||.:|....||:||.::|:    |...:.:||...|.||..| :.||....|.||    ||:..
  Rat   124 VNGINVENATHEEVVHLLRN----AGDVVTITVEYLREAPSFL-KLPLGSPGPSSD----HSSRA 179

  Fly   621 DGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKP----ANAPKNRYRDIS----P 677
             ...||...|.|                    |...:.|....|    ||.||...|.:.    |
  Rat   180 -SSPLFDSGLHL--------------------NGHCSHTAPSSPSSPIANEPKYEKRWLDTLSVP 223

  Fly   678 YDCTRVSLVNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHL----LV 738
            ....|:|...:.|....::....:.:.|.:..   |.|...|....|:.|.:....:.|    :.
  Rat   224 LSMARISRYKAGTEKLRSSALEVLALDGASTG---ALQFSTAQDCADWLRAISTNINELTLQHMK 285

  Fly   739 MLTTVMESGRQKCHQYWPVTGEELQLAE 766
            |.........|..|..|  ..|.||.|:
  Rat   286 MANKCCSPCDQVVHMGW--VNERLQGAD 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	28/86 (33%)
		Y_phosphatase	666..955	CDD:278528	23/109 (21%)
		PTPc	668..955	CDD:238006	22/107 (21%)
Sntg2	XP_006240029.1	PDZ_signaling	72..153	CDD:238492	28/85 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910