Protein Alignment Ptpmeg and pyp1

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_594885.1
• Gene: pyp1 / 2542677
• PomBaseID: SPAC26F1.10c
• Length: 550
• Species: Schizosaccharomyces pombe
• Alignment Length: 642
• Identity: 148/642 - (23%)
• Similarity: 228/642 - (35%)
• Gaps: 239/642 - (37%)

  Fly   387 PMQQHSGSESANSHNNGKPAGAGTILTITKTSRP-----------HD------------------ 422
            |:.:.|.|....|.|...||        |...||           ||
pombe    61 PVSEFSKSRIKGSVNLSLPA--------TLIKRPAFSVARIISNLHDVDDKRDFQNWQEFSSILV 117

  Fly   423 -------NKVTSKEA-DSMPRKAWEQQSDEYDIQLDVGFIEQCTRRFES------------ASPS 467
                   |.||:.|. ....||  |..|.::.| ||:.: .:.:.::.|            |.||
pombe   118 CVPAWIANYVTNAEVIGEKFRK--ESYSGDFGI-LDLDY-SKVSGKYPSVIDNSPVKSKLGALPS 178

  Fly   468 PMPP-AYSSGQHSPILLPTTIADAVGHQQPESGSDLITIRLQADEQGRYGFNVKGGVDLSLPVQV 531
            ..|. :||:.|.:||.|.:            .|||.                      .|.|
pombe   179 ARPRLSYSAAQTAPISLSS------------EGSDY----------------------FSRP--- 206

  Fly   532 SKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPL 596
                |.||                    :|.||........:.:.:...|.       |..||.:
pombe   207 ----PPTP--------------------NVAGLSLNNFFCPLPENKDNKSS-------PFGSATV 240

  Fly   597 LLEEEPLYQYVPES----DEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLA 657
               :.|....||::    |....:...|...:|..|.|:..||                :|...:
pombe   241 ---QTPCLHSVPDAFTNPDVATLYQKFLRLQSLEHQRLVSCSD----------------RNSQWS 286

  Fly   658 ITEARKPANAPKNRYRDISPYDCTRVSLVNSLTG--DYINANYVNMEIPGGAVNRYIATQGPLAS 720
            ..::....:..||||.||.||:||||.|..:...  |||||:::..|     .:.|||.||.::.
pombe   287 TVDSLSNTSYKKNRYTDIVPYNCTRVHLKRTSPSELDYINASFIKTE-----TSNYIACQGSISR 346

  Fly   721 TTTDFWRMV--QQESSHLLVMLTTVMESGRQKCHQYWPVTG-EELQLAEGFSVRCLSEKPDETGS 782
            :.:|||.||  ..|:...:|||.::.|:||:.|..|||..| .:.|:...:.|:.:||:..:...
pombe   347 SISDFWHMVWDNVENIGTIVMLGSLFEAGREMCTAYWPSNGIGDKQVYGDYCVKQISEENVDNSR 411

  Fly   783 FVFREFVLKDKH--EQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQV 845
            |:.|:|.:::.:  ..:.:||.||..|.|...|.:....:||.:.|..:.
pombe   412 FILRKFEIQNANFPSVKKVHHYQYPNWSDCNSPENVKSMVEFLKYVNNSH--------------- 461

  Fly   846 RLMDADADADENGGLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLI 910
                                   .:|.|                      |||||||:||||..|
pombe   462 -----------------------GSGNT----------------------IVHCSAGVGRTGTFI 481

  Fly   911 LMDTALALMEAR------------EPVYPLDIVRTMRDQRACMVQNVSQYRFVCECI 955
            ::||.|...|::            :.|:.|  |..:|.||..|||..:|:::|.:.|
pombe   482 VLDTILRFPESKLSGFNPSVADSSDVVFQL--VDHIRKQRMKMVQTFTQFKYVYDLI 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	9/86 (10%)
		Y_phosphatase	666..955	CDD:278528	87/307 (28%)
		PTPc	668..955	CDD:238006	87/305 (29%)
pyp1	NP_594885.1	RHOD	41..161	CDD:294087	23/111 (21%)
		COG5599	244..548	CDD:227886	98/376 (26%)
		PTPc	297..536	CDD:238006	87/305 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	148	1.000	Domainoid score	I1118
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000