Protein Alignment Ptpmeg and Pdzrn4

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_001158065.1
• Gene: Pdzrn4 / 239618
• MGIID: 3056996
• Length: 1014
• Species: Mus musculus
• Alignment Length: 557
• Identity: 103/557 - (18%)
• Similarity: 162/557 - (29%)
• Gaps: 245/557 - (43%)

  Fly   492 GHQQPESGSDLITIRLQADEQGRYGFNVKGG------VDLSLP--VQVSKVVPHTPADRCTPRVC 548
            |.|:|      .|:.|:. |....|||:.||      ...|.|  :.|||::.:.||||     .
Mouse   199 GEQKP------FTVVLER-EDDTLGFNIIGGRPYQNSQKQSAPEGIYVSKILENGPADR-----A 251

  Fly   549 EG----DEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPE 609
            :|    |:::.:||||:....||:.|...|..:..      :.|:..|..||   ..|.|...||
Mouse   252 DGLEVHDKIIAVNGRDLSKATHEEAVEAFRTAKEP------IVVQVLRRTPL---SRPTYGMTPE 307

  Fly   610 SDEIGSHSNLLDGDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRD 674
                                                                             
Mouse   308 ----------------------------------------------------------------- 307

  Fly   675 ISPYDCTRVSLVNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVM 739
               ...|..|....:|.::|.|               :|...||.....|....:..:|.|.|
Mouse   308 ---VQLTNASTQTDITFEHIMA---------------LAKLRPLTPPVPDTCPFLLSDSCHSL-- 352

  Fly   740 LTTVMESGRQKCHQY---WPVTG--------EELQLAE-------GFSVRCLSEKPDETGSFVFR 786
              ..||.|..:.|:|   .|...        ||::|..       |.:|...::..::||.:|..
Mouse   353 --HPMEHGFYEDHEYVSSLPADADRADDFEYEEVELCRVSSQEKLGLTVCYRTDDEEDTGIYVSE 415

  Fly   787 EFVLKDKHEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTL------LQEIEESL--- 842
                                       .|||.......|:|.. :|.|      :|..||::
Mouse   416 ---------------------------VDPNSIAAKDGRIREG-DRILQINGEDIQNREEAVALL 452

  Fly   843 -----KQVRLMDADAD-------------------------ADENGG-------LMRERKCAASN 870
                 |::.|:.|..|                         .|.|.|       |.:.:|.....
Mouse   453 SSDECKRIVLLIARPDMQLDEGWLEDERNEFLEELNSELLEEDHNEGAQRTASELQQPKKQEEEE 517

  Fly   871 GATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDT------------ALALMEARE 923
            |.|   :|..|:|.:|           ...:|:|||...:..|.            :..|...||
Mouse   518 GTT---DTATSSSNNQ-----------EKDSGVGRTDESLRNDESSEQENAVEEPHSTTLKSKRE 568

  Fly   924 PVYPLDIVRTMRDQRA-------CMVQNVSQYRFVCE 953
            .....|.:.::..|.:       |:..:.:..:.|||
Mouse   569 LGKSQDTLGSLEHQCSESCAGGECLDSDCASNQEVCE 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	27/98 (28%)
		Y_phosphatase	666..955	CDD:278528	65/371 (18%)
		PTPc	668..955	CDD:238006	65/369 (18%)
Pdzrn4	NP_001158065.1	RING	18..55	CDD:214546
		PDZ	202..294	CDD:214570	29/109 (27%)
		PDZ_signaling	383..465	CDD:238492	19/109 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910