Protein Alignment Ptpmeg and Mpp4

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_001158154.1
• Gene: Mpp4 / 227157
• MGIID: 2386681
• Length: 654
• Species: Mus musculus
• Alignment Length: 241
• Identity: 53/241 - (21%)
• Similarity: 91/241 - (37%)
• Gaps: 86/241 - (35%)

  Fly   480 PIL--LPTTIADA---------VGHQQP--------ESGSDLITIRLQADEQGRYGFNVKGGVDL 525
            |:|  ||..|.|:         |.:|||        |...|::..|:           :.||:
Mouse   154 PLLPPLPDNIPDSEEAMRIVCLVKNQQPLGATIKRHEITGDILVARV-----------IHGGL-- 205

  Fly   526 SLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVHGLRHEQVVAMIRDCRHQASGELLLTVRP 590
               |:.|.:            :..||:::.:||..|.||..|||:.::.    .:.|.::..|.|
Mouse   206 ---VERSGL------------LYAGDKLVEVNGVSVEGLDPEQVIHILA----MSCGTIMFKVIP 251

  Fly   591 QRSAPLLLEEEPLY-----QYVPESDE----IGSHSNLLDGDALFTQSLLLLSDGLASGALLAQY 646
            . |||.:..::.:|     .|.|:.|.    :.:....|.||.|               .::.|.
Mouse   252 V-SAPPVSSQKMVYVRAMIDYWPQEDPDIPCMDAGLPFLKGDIL---------------QIVDQN 300

  Fly   647 ELMY---RKNPDLAITEARKPAN-APKNRYRDI------SPYDCTR 682
            :.::   ||..||.|.....|:| ..|.:.|:.      .|:.|.:
Mouse   301 DALWWQARKISDLTICAGLIPSNHLLKRKQREFWWSQPYQPHTCLK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	16/86 (19%)
		Y_phosphatase	666..955	CDD:278528	5/24 (21%)
		PTPc	668..955	CDD:238006	4/21 (19%)
Mpp4	NP_001158154.1	L27	<66..100	CDD:197794
		L27	108..154	CDD:280918	53/241 (22%)
		PDZ_signaling	171..250	CDD:238492	22/110 (20%)
		SH3_MPP4	264..324	CDD:212967	15/74 (20%)
		Guanylate_kin	446..636	CDD:279019
		GuKc	454..637	CDD:214504

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910