DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ptpmeg and W01B6.6

DIOPT Version :9

Sequence 1:	NP_001163309.2	Gene:	Ptpmeg / 38059	FlyBaseID:	FBgn0261985	Length:	974	Species:	Drosophila melanogaster
Sequence 2:	NP_501827.3	Gene:	W01B6.6 / 189083	WormBaseID:	WBGene00012173	Length:	366	Species:	Caenorhabditis elegans

Alignment Length:	337	Identity:	65/337 - (19%)
Similarity:	123/337 - (36%)	Gaps:	81/337 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   622 GDALFTQSLLLLSDGLASGALLAQYELMYRKNPDLAITEARKPANAPKNRYRDISPYDCTRVSLV 686
            ||.  |...|:.|....:..:.:.::.:....|...:....|  |.||.......|....::..:
Worm    75 GDE--TAKKLVASGAFNTSTITSGFKELSNPKPSADMCSIFK--NNPKKSRAPDWPIADNKLIKL 135

  Fly   687 NSLTGDYINANYVNMEIPGGAVNR-YIATQGP---LASTTTDFWRMVQQESSHLLVMLTTVMESG 747
            :...|::|.|  ..:::|  ..|| .|.||.|   :::...|||||:.||....:|:....:|..
Worm   136 SHAPGNFICA--AKVDVP--EFNRTMIVTQIPDVTVSANIEDFWRMIFQEEIVSIVIAVMPLECS 196

  Fly   748 RQKCHQYWPVTGEELQLAEGFSVRCLSEKPDETGSFV-FREFVLKDKHEQRHIHHMQYL--AWPD 809
                     ||.::|             .|..:|:|. ..:..|.:|.....:....|.  ..||
Worm   197 ---------VTLQQL-------------FPLLSGTFSNHGKMFLNNKKVDSAVAMTAYTLEVLPD 239

  Fly   810 HCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENGGLMRERKCAASNGATP 874
            .|    .|..|.....:...:.:..|:.:.|.:..|
Worm   240 GC----SNSLLSTVYHLHNWKQKQGLENVGELVTTV----------------------------- 271

  Fly   875 EDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEAREPVYPLDIVRTMRDQRA 939
              |..:.|:.:..:.:.|         ||||.|.::.:.|::..::..:.|.|.:|:..:|.:|:
Worm   272 --EKVLKTNENTVLMSMN---------GIGRAGTMLTLFTSMLSVQKSKEVNPKEILIKLRGERS 325

  Fly   940 CMVQNVSQYRFV 951
            .:|:|..|:..|
Worm   326 GLVENADQFNTV 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492
		Y_phosphatase	666..955	CDD:278528	58/293 (20%)
		PTPc	668..955	CDD:238006	57/291 (20%)
W01B6.6	NP_501827.3	PTPc	97..342	CDD:214550	60/313 (19%)
W01B6.6	NP_501827.3	PTPc	118..342	CDD:304379	56/290 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910