Protein Alignment Ptpmeg and C46A5.1

DIOPT Version :9

• Sequence 1: NP_001163309.2
• Gene: Ptpmeg / 38059
• FlyBaseID: FBgn0261985
• Length: 974
• Species: Drosophila melanogaster
• Sequence 2: NP_501277.1
• Gene: C46A5.1 / 183497
• WormBaseID: WBGene00016698
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 616
• Identity: 121/616 - (19%)
• Similarity: 213/616 - (34%)
• Gaps: 223/616 - (36%)

  Fly   382 SSGGTPMQQH---SGSESANSHNNGKPAGAGTILTITKTSRPHDNKVTSKEADSMPRK------- 436
            :..||..:.|   |.|:|.|...||        |:..:..:....|..||.....|:|
 Worm    24 TGNGTAKKHHKRKSRSKSKNKPKNG--------LSCCRKKKKKSKKSKSKVTKKQPKKKVIKPLA 80

  Fly   437 -AWEQQSDEYDIQLDVGFIEQCTRRFESASPSPMPPAYSSGQHSPILLPTTIADAVGHQQPESGS 500
             ...:|..|..:..:|...|           :|..|...          |.:.|  |.:.|.:.:
 Worm    81 PVPNEQLGEVVLVKNVKLPE-----------TPQKPEND----------TPVKD--GLKPPRTTN 122

  Fly   501 DLITIRLQADEQGRYGFNV---KGGVDLSLPVQVSKVVPHTPADRCTPRVCEGDEVLMINGRDVH 562
            .:..|.|..:     .||:   |...|.....::.|....:|||     :.:|     :.|:.
 Worm   123 SVEKINLSKE-----SFNLSNEKIASDNGTEEKMEKKNVDSPAD-----IQDG-----LKGKS-- 170

  Fly   563 GLRHEQVVAMIRDCRHQASGELLLTVRPQRSAPLLLEEEPLYQYVPESDEIGSHSNLLDGDALFT 627
                                       .|:|      ||.::|...:..:.|...|
 Worm   171 ---------------------------KQKS------EEKVHQKAKDDAKRGDECN--------- 193

  Fly   628 QSLLLLSDGLASGALLAQYELMYRKNPDLAITEARK--------------PANAPKNRYRDISPY 678
             ...:..:.|....|:||..|  :.:.::|:.|..|              .:|..|||:.|:...
 Worm   194 -KFKISDEKLTKWKLVAQETL--KDDANIAVNEFEKVSGYLPPHISKNHFVSNMDKNRFVDVICM 255

  Fly   679 DCTRVSLVNSLTGDYINANYVNMEIPGGAVNRYIATQGPLASTTTDFWRMVQQESSHLLVMLTTV 743
            |.:||.|.:|   .||:||:|::    .:..:.|.||.||:.|.:|||:|:..:....::::.|.
 Worm   256 DHSRVKLTDS---SYIHANWVDL----NSSKKAILTQLPLSHTASDFWQMIIDQKIKCVLLIMTD 313

  Fly   744 MESGRQKCHQYWPV-------------TGE--ELQLAEGFSVRCLSEKPDETGSFVFREFVLKDK 793
            .|..:...:..:|.             .||  :::|.:|::::.||     ..:..::.|:
 Worm   314 GEFNKFGGNSVFPQNQDFLKFEDRFIRVGEFKQVELGKGWNLKVLS-----VSNGTYKTFI---- 369

  Fly   794 HEQRHIHHMQYLAWPDHCVPSDPNLFLEFTERVRAARNRTLLQEIEESLKQVRLMDADADADENG 858
                |:||  |..||...:|||                          :||:..:.:......:|
 Worm   370 ----HVHH--YKNWPHGSIPSD--------------------------VKQIWQVQSYLRKYTDG 402

  Fly   859 GLMRERKCAASNGATPEDETPVSTSVHQCISAANPPVIVHCSAGIGRTGVLILMDTALALMEARE 923
                                             :|||.:..| |.||.|...|.:||...:...:
 Worm   403 ---------------------------------HPPVYMSMS-GCGRAGTFALFETAHMSLHNEQ 433

  Fly   924 PVYPLDIVR---TMRDQRACMVQNVSQYRFV 951
            |  .|::|:   .:|:.|...|||:||:..|
 Worm   434 P--SLNMVKCLENVRNGRLHSVQNLSQFSVV 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptpmeg	NP_001163309.2	B41	35..232	CDD:214604
		FERM_N	38..102	CDD:286467
		FERM_M	125..232	CDD:278785
		FERM_C_PTPN4_PTPN3_like	226..320	CDD:270010
		FA	333..369	CDD:285894
		PDZ_signaling	502..589	CDD:238492	12/89 (13%)
		Y_phosphatase	666..955	CDD:278528	69/304 (23%)
		PTPc	668..955	CDD:238006	68/302 (23%)
C46A5.1	NP_501277.1	Y_phosphatase	243..468	CDD:278528	69/304 (23%)
		PTPc	245..468	CDD:238006	68/302 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910